Serum tryptophan and kynurenine concentrations as parameters for indoleamine 2, 3-dioxygenase activity in patients with endometrial, ovarian, and vulvar cancer

RA de Jong, HW Nijman, HM Boezen… - International Journal of …, 2011 - ijgc.bmj.com
Objective: Indoleamine 2, 3-dioxygenase (IDO) suppresses the function of T-lymphocytes
and is involved in immune escape of cancers. Indoleamine 2, 3-dioxygenase catalyzes the …
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Delaying aging and the aging-associated decline in protein homeostasis by inhibition of tryptophan degradation

AT Van Der Goot, W Zhu… - Proceedings of the …, 2012 - National Acad Sciences
Toxicity of aggregation-prone proteins is thought to play an important role in aging and age-
related neurological diseases like Parkinson and Alzheimer's diseases. Here, we identify …
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