Alzheimer's disease (AD) is characterized by deficits in cerebral metabolic rates of glucose
in the posterior cingulate (PC) and precuneus in AD subjects, and in APOEε4 carriers …

Human infection with the protozoan parasite Trypanosoma cruzi causes Chagas disease for
which there are no prophylactic vaccines. Cyclophilin 19 is a secreted cis-trans peptidyl …

African trypanosomes utilize glycosylphosphatidylinositol (GPI)-anchored variant surface
glycoprotein (VSG) to evade the host immune system. VSG turnover is thought to be …

Arginine homeostasis in lysosomes is critical for the growth and metabolism of mammalian
cells. Phagolysosomes of macrophages are the niche where the parasitic protozoan …

Balamuthia mandrillaris, a pathogenic free-living amoeba, causes cutaneous skin lesions as
well as granulomatous amoebic encephalitis, a 'brain-eating'disease. As with the other …

Disease outbreaks, skin lesions, mortality events, and reproductive abnormalities have been
observed in wild populations of centrarchids. The presence of estrogenic endocrine …

Objective: This cross-sectional study utilized structural equation modeling to examine effects
of COVID-19 stress on food insecurity and fruit and vegetable consumption mediated …

Unlike most other eukaryotes, Leishmania and other trypanosomatid protozoa have largely
eschewed transcriptional control of gene expression, relying instead on posttranscriptional …

Monoallelic exclusion ensures that the African trypanosome Trypanosoma brucei
exclusively expresses only 1 of thousands of different variant surface glycoprotein (VSG) …

DNA focused panel sequencing has been rapidly adopted to assess therapeutic targets in
advanced/refractory cancer. Integrated Genomic Profiling (IGP) utilising DNA/RNA with …