▪ Abstract The 3-phosphorylated inositol lipids fulfill roles as second messengers by
interacting with the lipid binding domains of a variety of cellular proteins. Such interactions …

▪ Abstract The phosphoinositide 3-kinase (PI3K) family of enzymes is recruited upon growth
factor receptor activation and produces 3′ phosphoinositide lipids. The lipid products of …

DIGE is a protein labelling and separation technique allowing quantitative proteomics of two
or more samples by optical fluorescence detection of differentially labelled proteins that are …

The PI3Ks (phosphatidylinositol 3-kinases) regulate cellular signalling networks that are
involved in processes linked to the survival, growth, proliferation, metabolism and …

COVID-19 is highly variable in its clinical presentation, ranging from asymptomatic infection
to severe organ damage and death. We characterized the time-dependent progression of …

Hepatitis C virus (HCV) cell entry involves interaction between the viral envelope
glycoprotein E2 and the cell surface receptor CD81. Knowledge of conserved E2 …

Background: Periodontitis is a bacterial disease modified by multiple risk factors. The pro‐
inflammatory cytokine interleukin‐1 (IL‐1) is a key regulator of the host responses to …

Fibrosing alveolitis (FA) is characterized by persistent inflammation and elevated production
of tumor necrosis factor-alpha (TNF-α), interleukin-1 beta (IL-1 β), and interleukin-1 receptor …

The technique of fluorescent two-dimensional (2D) difference gel electrophoresis for
differential protein expression analysis has been evaluated using a model breast cancer cell …

Purpose: Biomarkers for the early detection of pancreatic cancer are urgently needed. The
primary objective of this study was to evaluate whether increased levels of serum CA19-9 …