Fracture risk and management of discontinuation of denosumab therapy: a systematic review and position statement by ECTS

…, SH Ralston, R Eastell, J Pepe… - The Journal of …, 2021 - academic.oup.com
Context Denosumab discontinuation is characterized by an increase in bone turnover
overriding pretreatment status, a rapid bone loss in the majority and multiple vertebral …

The diagnosis and management of hypercalcaemia

S Minisola, J Pepe, S Piemonte, C Cipriani - Bmj, 2015 - bmj.com
Hypercalcaemia is a common finding in the setting of primary care, 1 as well as in
emergency departments2 and patients admitted to hospital. 3 Primary hyperparathyroidism …

Tumour-induced osteomalacia

…, M Peacock, S Fukumoto, C Cipriani, J Pepe… - Nature reviews Disease …, 2017 - nature.com
Abstract Tumour-induced osteomalacia (TIO), also known as oncogenic osteomalacia, is a
rare paraneoplastic disorder caused by tumours that secrete fibroblast growth factor 23 …

Yersinia enterocolitica invasin: a primary role in the initiation of infection.

JC Pepe, VL Miller - … of the National Academy of Sciences, 1993 - National Acad Sciences
The ability to invade the intestinal epithelium of mammals is an essential virulence
determinant of Yersinia enterocolitica. The chromosomally encoded Y. enterocolitica 8081v …

Prevalence of kidney stones and vertebral fractures in primary hyperparathyroidism using imaging technology

…, C Zhang, P Biondi, D Diacinti, J Pepe… - The Journal of …, 2015 - academic.oup.com
Context: The fourth International Workshop on the Management of Asymptomatic Primary
Hyperparathyroidism (PHPT) has recently suggested that skeletal and renal imaging be …

Structural basis of omega-3 fatty acid transport across the blood–brain barrier

RJ Cater, GL Chua, SK Erramilli, JE Keener, BC Choy… - Nature, 2021 - nature.com
Docosahexaenoic acid is an omega-3 fatty acid that is essential for neurological
development and function, and it is supplied to the brain and eyes predominantly from …

Growth phase and low pH affect the thermal regulation of the Yersinia enterocolitica inv gene

JC Pepe, JL Badger, VL Miller - Molecular microbiology, 1994 - Wiley Online Library
The inv gene encodes the protein invasin, which is the primary invasion factor for Yersinia
enterocolitica in vitro and in vivo. Previous studies of Yersinia species have shown that inv …

“Trabecular Bone Score”(TBS): an indirect measure of bone micro-architecture in postmenopausal patients with primary hyperparathyroidism

…, I Nofroni, C Castro, M Angelozzi, A Scarpiello, J Pepe… - Bone, 2013 - Elsevier
BACKGROUND: Patients with primary hyperparathyroidism (PHPT) generally show reduced
bone mineral density (BMD) at cortical sites with relatively preserved trabecular bone …

Cardiovascular manifestations of primary hyperparathyroidism: a narrative review

J Pepe, C Cipriani, C Sonato, O Raimo… - European Journal of …, 2017 - academic.oup.com
Data on cardiovascular disease in primary hyperparathyroidism (PHPT) are controversial;
indeed, at present, cardiovascular involvement is not included among the criteria needed for …

[HTML][HTML] The interplay between bone and glucose metabolism

…, M Mastrantonio, S Minisola, J Pepe - Frontiers in …, 2020 - frontiersin.org
The multiple endocrine functions of bone other than those related to mineral metabolism,
such as regulation of insulin sensitivity, glucose homeostasis, and energy metabolism, have …