User profiles for "author:J Herod"

Jonathan Herod

Director of Transformation, Hamad Medical Corporation Women's Hospital
Verified email at hamad.qa
Cited by 6064

[HTML][HTML] Ovarian cancer screening and mortality in the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS): a randomised controlled trial

…, K Godfrey, R Gunu, M Habib, R Hallett, J Herod… - The Lancet, 2016 - thelancet.com
Background Ovarian cancer has a poor prognosis, with just 40% of patients surviving 5
years. We designed this trial to establish the effect of early detection by screening on ovarian …

Primary chemotherapy versus primary surgery for newly diagnosed advanced ovarian cancer (CHORUS): an open-label, randomised, controlled, non-inferiority trial

…, S Dobbs, S Essapen, J Twigg, J Herod… - The Lancet, 2015 - thelancet.com
Background The international standard of care for women with suspected advanced ovarian
cancer is surgical debulking followed by platinum-based chemotherapy. We aimed to …

[HTML][HTML] Sensitivity and specificity of multimodal and ultrasound screening for ovarian cancer, and stage distribution of detected cancers: results of the prevalence …

…, A Lopes, K Godfrey, D Oram, J Herod… - The lancet …, 2009 - thelancet.com
Background Ovarian cancer has a high case–fatality ratio, with most women not diagnosed
until the disease is in its advanced stages. The United Kingdom Collaborative Trial of …

Radical vaginal trachelectomy as a fertility‐sparing procedure in women with early‐stage cervical cancer—cumulative pregnancy rate in a series of 123 women

JH Shepherd, C Spencer, J Herod… - BJOG: An International …, 2006 - Wiley Online Library
Objective To analyse the fertility rates, complications and recurrences in a group of women
who have undergone radical vaginal trachelectomy and pelvic lymphadenectomy for early …

The control of apoptosis and drug resistance in ovarian cancer: influence of p53 and Bcl-2.

AG Eliopoulos, DJ Kerr, J Herod, L Hodgkins… - Oncogene, 1995 - europepmc.org
Modulation of apoptosis may influence resistance to chemotherapy and therefore affect the
outcome of cancer treatment. Ovarian cancer, one of the most fatal malignancies in women …

[HTML][HTML] Sensitivity of transvaginal ultrasound screening for endometrial cancer in postmenopausal women: a case-control study within the UKCTOCS cohort

…, K Ford, K Godfrey, A Lopes, D Oram, J Herod… - The lancet …, 2011 - thelancet.com
Background The increase in the worldwide incidence of endometrial cancer relates to rising
obesity, falling fertility, and the ageing of the population. Transvaginal ultrasound (TVS) is a …

[HTML][HTML] Risk algorithm using serial biomarker measurements doubles the number of screen-detected cancers compared with a single-threshold rule in the United …

…, K Godfrey, A Lopes, D Oram, J Herod… - Journal of Clinical …, 2015 - ncbi.nlm.nih.gov
Risk Algorithm Using Serial Biomarker Measurements Doubles the Number of Screen-Detected
Cancers Compared With a Single-Threshold Rule in the United Kingdom Collaborative Trial of …

The prognostic significance of Bcl-2 and p53 expression in ovarian carcinoma

JJO Herod, AG Eliopoulos, J Warwick, G Niedobitek… - Cancer Research, 1996 - AACR
Advanced ovarian cancer is characterized by poor prognosis and the development of
resistance to chemotherapy. We have found that Bcl-2 and p53, two proteins implicated in …

Recruitment to multicentre trials—lessons from UKCTOCS: descriptive study

…, S Lewis, A Lopez, K Godfrey, D Oram, J Herod… - Bmj, 2008 - bmj.com
Objective To describe the factors that contributed to successful recruitment of more than 200
000 women to the UK Collaborative Trial of Ovarian Cancer Screening, one of the largest …

Risk of epithelial ovarian cancer in asymptomatic women with ultrasound‐detected ovarian masses: a prospective cohort study within the UK collaborative trial of …

…, R Rangar, K Godfrey, D Oram, J Herod… - … in obstetrics & …, 2012 - Wiley Online Library
Objective To estimate the risk of primary epithelial ovarian cancer (EOC) and slow growing
borderline or Type I and aggressive Type II EOC in postmenopausal women with adnexal …