Currently, the search for new promising tools of immunotherapy continues. In this regard,
microRNAs (miRNAs) that influence immune checkpoint (IC) gene expression in tumor and …

Background Evidence has accumulated showing that an increase in thyroid cancer
incidence reflects overdiagnosis of clinically unimportant lesions due to the rise in the use of …

Adenocarcinomas of the gastrointestinal tract (esophagus, stomach, and colon) represent a
heterogeneous group of diseases with distinct etiology, clinical features, treatment …

Objective: To examine the efficacy of the Ivor Lewis esophagectomy with extended 2-field
lymph node dissection for thoracic esophageal carcinoma we reviewed our experience …

Sequential courses of anticancer target therapy lead to selection of drug-resistant cells,
which results in continuous decrease of clinical response. Here we present a new approach …

Our work aimed to differentiate 20 aberrantly methylated miRNA genes that participate at
different stages of development and metastasis of ovarian carcinoma (OvCa) using …

Simple Summary Gastric cancer (GC) is one of the most common cancers and the fifth
leading cause of cancer-related deaths worldwide. The steadily growing interest in secreted …

In the immunotherapy based on immune checkpoint inhibition (IC), additional ICs are being
studied to increase its effectiveness. An almost unstudied feature is the possible co …

Simple Summary Renal cell carcinoma (RCC) is one of the most common cancer types.
However, the lack of clinical symptoms and validated biomarkers for early stage RCC …

Discussants: Please provide details as to what should be the initial evaluation of a patient
with this presentation The initial evaluation in this patient should include a computed …