[HTML][HTML] Hormone receptor loss in endometrial carcinoma curettage predicts lymph node metastasis and poor outcome in prospective multicentre trial

J Trovik, E Wik, HMJ Werner, C Krakstad… - European journal of …, 2013 - Elsevier
Background Preoperative histologic examination of tumour tissue is essential when deciding
if endometrial cancer surgery should include lymph node sampling. We wanted to …

Stathmin overexpression identifies high-risk patients and lymph node metastasis in endometrial cancer

J Trovik, E Wik, IM Stefansson, J Marcickiewicz… - Clinical cancer …, 2011 - AACR
Purpose: Overexpression of the oncogen Stathmin has been linked to aggressive
endometrial carcinoma and a potential for PI3Kinase inhibitors in this disease. We wanted to …

[HTML][HTML] Progesterone inhibits epithelial-to-mesenchymal transition in endometrial cancer

PH van der Horst, Y Wang, I Vandenput, LC Kühne… - PLoS …, 2012 - journals.plos.org
Background Every year approximately 74,000 women die of endometrial cancer, mainly due
to recurrent or metastatic disease. The presence of tumor infiltrating lymphocytes (TILs) as …

High-throughput interrogation of PIK3CA, PTEN, KRAS, FBXW7 and TP53 mutations in primary endometrial carcinoma

DA Garcia-Dios, D Lambrechts, L Coenegrachts… - Gynecologic …, 2013 - Elsevier
OBJECTIVE: Endometrial cancer patients may benefit from systemic adjuvant
chemotherapy, alone or in combination with targeted therapies. Prognostic and predictive …

Synchronous ovarian and endometrial cancer—an international multicenter case-control study

F Heitz, F Amant, C Fotopoulou, MJ Battista… - International Journal of …, 2014 - ijgc.bmj.com
Objectives This study aimed to compare the prognosis of patients with synchronous
endometrial and ovarian cancer (SEOC) to matched controls with either endometrial cancer …

Opportunistic salpingectomy in women undergoing hysterectomy: results from the HYSTUB randomised controlled trial

LAM Van Lieshout, B Pijlman, MC Vos, MJM de Groot… - Maturitas, 2018 - Elsevier
Objective To evaluate whether opportunistic salpingectomy in premenopausal women
undergoing hysterectomy for benign indications is both hormonally and surgically safe …

[HTML][HTML] PIpelle Prospective ENDOmetrial carcinoma (PIPENDO) study, pre-operative recognition of high risk endometrial carcinoma: a multicentre prospective cohort …

NCM Visser, J Bulten, AAM van der Wurff, EA Boss… - BMC cancer, 2015 - Springer
Background Endometrial carcinoma is the most common gynaecologic malignancy in
industrialised countries and the incidence is still rising. Primary treatment is based on …

Evolution in endometrial cancer: evidence from an immunohistochemical study

I Vandenput, J Trovik, K Leunen, E Wik… - International Journal of …, 2011 - ijgc.bmj.com
Background: It is poorly described how endometrial cancer biology changes during tumor
evolution. We hypothesize that characterization of molecular targets in recurrent lesions is …

The role of adjuvant chemotherapy in surgical stages I-II serous and clear cell carcinomas and carcinosarcoma of the endometrium: a collaborative study

I Vandenput, J Trovik, I Vergote, P Moerman… - International Journal of …, 2011 - ijgc.bmj.com
Objective: To assess the impact of adjuvant chemotherapy in early surgically staged type II
endometrial cancer (serous [S], clear cell carcinoma [CC]) and carcinosarcomas (CS) on …

Leuven dose-dense paclitaxel/carboplatin regimen in patients with primary advanced or recurrent endometrial carcinoma

I Vandenput, I Vergote, K Leunen, P Berteloot… - International Journal of …, 2009 - ijgc.bmj.com
Objective: To evaluate the response of dose-dense paclitaxel/carboplatin (TC) patients with
primarily advanced or recurrent endometrial cancer. Methods: Six courses of paclitaxel (90 …