[PDF][PDF] Tracking cancer evolution reveals constrained routes to metastases: TRACERx renal
Clear-cell renal cell carcinoma (ccRCC) exhibits a broad range of metastatic phenotypes
that have not been systematically studied to date. Here, we analyzed 575 primary and 335 …
that have not been systematically studied to date. Here, we analyzed 575 primary and 335 …
Biomarkers in bladder cancer
I Proctor, K Stoeber, GH Williams - Histopathology, 2010 - Wiley Online Library
Proctor I, Stoeber K & Williams GH (2010) Histopathology 57, 1–13 Biomarkers in bladder
cancer Cancer biomarkers provide an opportunity to diagnose tumours earlier and with …
cancer Cancer biomarkers provide an opportunity to diagnose tumours earlier and with …
[PDF][PDF] Determinants of anti-PD-1 response and resistance in clear cell renal cell carcinoma
ADAPTeR is a prospective, phase II study of nivolumab (anti-PD-1) in 15 treatment-naive
patients (115 multiregion tumor samples) with metastatic clear cell renal cell carcinoma …
patients (115 multiregion tumor samples) with metastatic clear cell renal cell carcinoma …
Non-perforating small bowel Crohn's disease assessed by MRI enterography: derivation and histopathological validation of an MR-based activity index
MJ Steward, S Punwani, I Proctor… - European journal of …, 2012 - Elsevier
OBJECTIVES: To develop and validate a qualitative scoring system for enteric Crohn's
disease activity using MR enterography (MRE). METHODS: MRE was performed in 16 …
disease activity using MR enterography (MRE). METHODS: MRE was performed in 16 …
Late-stage metastatic melanoma emerges through a diversity of evolutionary pathways
Understanding the evolutionary pathways to metastasis and resistance to immune-
checkpoint inhibitors (ICI) in melanoma is critical for improving outcomes. Here, we present …
checkpoint inhibitors (ICI) in melanoma is critical for improving outcomes. Here, we present …
Quantified terminal ileal motility during MR enterography as a potential biomarker of Crohn's disease activity: a preliminary study
Objective To compare quantified terminal ileal (TI) motility during MR enterography (MRE)
with histopathological severity of acute inflammation in Crohn's disease. Methods A total of …
with histopathological severity of acute inflammation in Crohn's disease. Methods A total of …
[PDF][PDF] Representative sequencing: unbiased sampling of solid tumor tissue
K Litchfield, S Stanislaw, L Spain, LL Gallegos… - Cell reports, 2020 - cell.com
Although thousands of solid tumors have been sequenced to date, a fundamental under-
sampling bias is inherent in current methodologies. This is caused by a tissue sample input …
sampling bias is inherent in current methodologies. This is caused by a tissue sample input …
Importance of expert central review in the diagnosis of lymphoid malignancies in a regional cancer network
IE Proctor, C McNamara, M Rodriguez-Justo… - Journal of Clinical …, 2011 - ascopubs.org
Purpose The accurate diagnosis of hematologic malignancies remains a challenging area
for histopathologists. In 2003, the North Central London Lymphoma network was …
for histopathologists. In 2003, the North Central London Lymphoma network was …
[HTML][HTML] Targeting DNA replication before it starts: Cdc7 as a therapeutic target in p53-mutant breast cancers
S Rodriguez-Acebes, I Proctor, M Loddo… - The American journal of …, 2010 - Elsevier
Treatment options for triple-receptor negative (ER−/PR−/Her2−) and Her2-overexpressing
(ER−/PR−/Her2+) breast cancers with acquired or de novo resistance are limited, and …
(ER−/PR−/Her2+) breast cancers with acquired or de novo resistance are limited, and …
CD4+ T cell down-regulation in human intestinal mucosa: evidence for intestinal tolerance to luminal bacterial antigens.
UY Khoo, IE Proctor, AJ Macpherson - Journal of immunology …, 1997 - journals.aai.org
T cells from the intestinal mucosal proliferate poorly in vitro, and the contribution of Ag-
specific recognition to this hyporesponsiveness is unclear, since the Ag repertoire of …
specific recognition to this hyporesponsiveness is unclear, since the Ag repertoire of …