Molecular targets for the therapy of cancer associated with metabolic syndrome (transcription and growth factors)

NV Yunusova, IV Kondakova… - Asia‐Pacific Journal …, 2018 - Wiley Online Library
Metabolic syndrome (MS) is one of the leading risk factors for the development of
cardiovascular diseases, type II diabetes mellitus and reproductive system diseases …

[HTML][HTML] Estrogen receptors and ubiquitin proteasome system: mutual regulation

IV Kondakova, EE Shashova, EA Sidenko… - Biomolecules, 2020 - mdpi.com
This review provides information on the structure of estrogen receptors (ERs), their
localization and functions in mammalian cells. Additionally, the structure of proteasomes and …

The role of metabolic syndrome variant in the malignant tumors progression

NV Yunusova, IV Kondakova, LA Kolomiets… - Diabetes & Metabolic …, 2018 - Elsevier
Metabolic syndrome (MS) is one of the leading risk factors for the development of some
common cancers (endometrial cancer, postmenopausal breast cancer, colorectal cancer) …

Superspin glass phase and hierarchy of interactions in multiferroic PbFe1/2Sb1/2O3: an analog of ferroelectric relaxors?

VV Laguta, VA Stephanovich, M Savinov… - New Journal of …, 2014 - iopscience.iop.org
We have fabricated new perovskite multiferroic PbFe $ _ {1/2} $ Sb $ _ {1/2} $ O 3 with a
high degree (up to 0.9) of chemical ordering and unexpectedly high-temperature magnetic …

Electron spin resonance investigation of ions and their dynamics in Mn-doped

VV Laguta, IV Kondakova, IP Bykov, MD Glinchuk… - Physical Review B, 2007 - APS
Using electron spin resonance (ESR), the lattice position and dynamic properties of Mn 2+
ions were studied in 0.5 and 2 at.% manganese-doped Sr Ti O 3 ceramics prepared by the …

[HTML][HTML] Proteasome functioning in breast cancer: connection with clinical-pathological factors

EE Shashova, YV Lyupina, SA Glushchenko… - PLoS …, 2014 - journals.plos.org
Breast cancer is one of four oncology diseases that are most widespread in the world.
Moreover, breast cancer is one of leading causes of cancer-related deaths in female …

Expression of vascular endothelial growth factor and transcription factors HIF-1, NF-kB expression in squamous cell carcinoma of head and neck; association with …

LV Spirina, IV Kondakova, EL Choynzonov… - Journal of cancer …, 2013 - Springer
Introduction The transcription factors NF-kB, HIF-1 and vascular endothelial growth factors
(VEGF) are known to play an important role in pathogenesis of squamous cell carcinoma of …

Association of growth factors, HIF-1 and NF-κB expression with proteasomes in endometrial cancer

LV Spirina, NV Yunusova, IV Kondakova… - Molecular biology …, 2012 - Springer
Insulin-like growth factors (IGFs), vascular endothelial growth factor (VEGF), hypoxia-
inducible factor-1 (HIF-1), and nuclear factor kappa-B (NF-κB) are known to play an …

Adenylyl cyclase-associated protein 1: structure, regulation, and participation in cellular processes

GV Kakurina, ES Kolegova, IV Kondakova - Biochemistry (Moscow), 2018 - Springer
This review summarizes information available to date about the structural organization,
regulation of functional activity of adenylyl cyclase-associated protein 1 (CAP1), and its …

The role of exosomal tetraspanins and proteases in tumor progression

NV Yunusova, EA Tugutova, SN Tamkovich… - … ), Supplement Series B …, 2018 - Springer
Abstract Major (CD9, CD63, CD81) and other (CD82, CD151, Tspan8) exosomal
tetraspanins interact with various proteins and form functional tetraspanin complexes in …