Abstract Heme oxygenase-1 (HO-1) system catalyzes heme to biologically active products:
carbon monoxide, biliverdin/bilirubin and free iron. It is involved in maintaining cellular …

Osteogenic differentiation of mesenchymal stem cells (MSCs) is a complex process, which is
regulated by various factors including microRNAs. Our preliminary data showed that the …

MTOR, a central regulator of autophagy, is involved in cancer and cardiovascular and
neurological diseases. Modulating the MTOR signaling balance could be of great …

MicroRNA deregulation and pathway alterations have been implicated in nasopharyngeal
carcinoma (NPC), a highly invasive and metastatic cancer widely prevalent in Southern …

We previously found that Homeobox containing 1 (HMBOX1) was required for bone
mesenchymal stem cell (BMSC) and mouse embryonic stem cell (ESC) differentiation into …

Abstract Heme oxygenase-1 (HO-1) system catabolizes heme into three products: carbon
monoxide, biliverdin/bilirubin and free iron. It is involved in many physiological and …

Background Glucose-regulated protein 78 (GRP78) is involved in not only the progression of
non-small cell lung cancer (NSCLC) but also chemotherapeutic effects. We hypothesized …

Macroautophagy (referred to as autophagy) is an evolutionarily conserved, bulk-destruction
process in eukaryotes. During this process, the cytoplasm containing long-lived proteins and …

Nuclear factor-erythroid 2-related factor 2 (Nrf2) is persistently activated in many human
tumors including acute myeloid leukemia (AML). Therefore, inhibition of Nrf2 activity may be …

Abstract Glucose-regulated protein 78 (GRP78) is one of the most important responders to
disease-related stress. We assessed the association of the promoter polymorphisms of …