Mutations in PTEN Are Frequent in Endometrial Carcinoma But Rare in Other Common Gynecological Malignancies

H Tashiro, MS Blazes, R Wu, KR Cho, S Bose, SI Wang… - Cancer research, 1997 - AACR
Loss of heterozygosity of chromosome 10q has been reported in approximately 40% of
endometrial carcinomas. PTEN, a candidate tumor suppressor gene located at chromosome …

The frequency of p53, k‐ras mutations, and microsatellite instability differs in uterine endometrioid and serous carcinoma: Evidence of distinct molecular genetic …

SF Lax, B Kendall, H Tashiro, RJC Slebos… - Cancer, 2000 - Wiley Online Library
BACKGROUND The two most common types of uterine endometrial carcinoma,
endometrioid (UEC) and serous (USC), differ in their histopathologic appearance and …

p53 gene mutations are common in uterine serous carcinoma and occur early in their pathogenesis.

H Tashiro, C Isacson, R Levine… - The American journal …, 1997 - ncbi.nlm.nih.gov
Uterine serous carcinoma (USC) is an uncommon but aggressive type of endometrial cancer
associated with rapid progression of disease and a poor prognosis. Both USC and its …

Involvement of M2‐polarized macrophages in the ascites from advanced epithelial ovarian carcinoma in tumor progression via Stat3 activation

K Takaishi, Y Komohara, H Tashiro, H Ohtake… - Cancer …, 2010 - Wiley Online Library
Ascites macrophages in advanced epithelial ovarian cancer (AdEOC) are involved in cancer
metastasis and progression by modifying the tumor microenvironment. However, the precise …

[HTML][HTML] Gene expression profile for predicting survival in advanced-stage serous ovarian cancer across two independent datasets

K Yoshihara, A Tajima, T Yahata, S Kodama… - PloS one, 2010 - journals.plos.org
Background Advanced-stage ovarian cancer patients are generally treated with
platinum/taxane-based chemotherapy after primary debulking surgery. However, there is a …

Japan Society of Gynecologic Oncology guidelines 2017 for the treatment of uterine cervical cancer

Y Ebina, M Mikami, S Nagase, T Tabata… - International journal of …, 2019 - Springer
Abstract The Japan Society of Gynecologic Oncology (JSGO) Guidelines 2017 for the
Treatment of Uterine Cervical Cancer are for the purpose of providing standard treatment …

Adnexal masses: accuracy of characterization with transvaginal US and precontrast and postcontrast MR imaging.

Y Yamashita, M Torashima, Y Hatanaka, M Harada… - Radiology, 1995 - pubs.rsna.org
PURPOSE: To determine the accuracy of transvaginal ultrasound (TVUS) and of precontrast
and contrast material-enhanced magnetic resonance (MR) imaging in the differentiation of …

Oncogenic transformation of human ovarian surface epithelial cells with defined cellular oncogenes

R Sasaki, M Narisawa-Saito, T Yugawa… - …, 2009 - academic.oup.com
Ovarian surface epithelium (OSE) is considered to give rise to epithelial ovarian carcinomas
(EOCs). To elucidate early processes contributing to the development of EOCs from the …

YAP1 is a potent driver of the onset and progression of oral squamous cell carcinoma

H Omori, M Nishio, M Masuda, Y Miyachi, F Ueda… - Science …, 2020 - science.org
Head-and-neck squamous cell carcinoma (HNSCC) is the sixth most common group of
cancers in the world, and patients have a poor prognosis. Here, we present data indicating …

[HTML][HTML] The impact of EpCAM expression on response to chemotherapy and clinical outcomes in patients with epithelial ovarian cancer

S Tayama, T Motohara, D Narantuya, C Li, K Fujimoto… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Epithelial ovarian cancer is a highly lethal malignancy; moreover, overcoming
chemoresistance is the major challenging in treating ovarian cancer patients. The cancer …