Rather than primary solid tumors, metastasis is one of the hallmarks of most cancer deaths.
Metastasis is a multistage event in which cancer cells escape from the primary tumor survive …

Ovarian cancer is the deadliest gynecological cancer, leading to over 152,000 deaths each
year. A late diagnosis is the primary factor causing a poor prognosis of ovarian cancer and …

Objective The objective of this study was to provide a consensus review on gestational
trophoblastic disease diagnosis and management from the combined International Society …

Gestational trophoblastic disease (GTD) arises from abnormal placenta and is composed of
a spectrum of premalignant to malignant disorders. Changes in epidemiology of GTD have …

To investigate the potential role of somatic mitochondrial DNA (mtDNA) mutations in
tumorigenesis, the occurrence of mutations in mtDNA of ovarian carcinomas was studied …

Gestational trophoblastic disease (GTD) arises from abnormal placenta and is composed of
a spectrum of premalignant to malignant disorders. Changes in epidemiology of GTD have …

Aberrant activation of hedgehog (HH) pathway has been implicated in the development of
human malignancies. This study aimed at investigating the role of HH molecules in human …

Abstract The RAS-RAF-MEK-extracellular signal-regulated kinase (ERK) pathway plays a
pivotal role in various cellular responses, including cellular growth, differentiation, survival …

The limitations of current anti-angiogenic therapies necessitate other targets with
complimentary mechanisms. Here, we show for the first time that soluble E-cadherin (sE …

Rationale: Malignant ascites in peritoneal metastases is a lipid-enriched microenvironment
and is frequently involved in the poor prognosis of epithelial ovarian cancer (EOC) …