User profiles for "author:H. Yoshida"

Hiderou Yoshida

University of Hyogo
Verified email at sci.u-hyogo.ac.jp
Cited by 24491

ER stress and diseases

H Yoshida - The FEBS journal, 2007 - Wiley Online Library
Proteins synthesized in the endoplasmic reticulum (ER) are properly folded with the
assistance of ER chaperones. Malfolded proteins are disposed of by ER‐associated protein …

IL-6/IL-6 receptor system and its role in physiological and pathological conditions

M Mihara, M Hashizume, H Yoshida, M Suzuki… - Clinical …, 2012 - portlandpress.com
IL (interleukin)-6, which was originally identified as a B-cell differentiation factor, is a
multifunctional cytokine that regulates the immune response, haemopoiesis, the acute …

Neuroprotective effects of edaravone: a novel free radical scavenger in cerebrovascular injury

H Yoshida, H Yanai, Y Namiki… - CNS drug …, 2006 - Wiley Online Library
Recanalization and neuroprotection have been mainly targeted for the specific treatment of
acute ischemic stroke. Free radicals play a crucial role in brain ischemic injury by …

Interferon therapy reduces the risk for hepatocellular carcinoma: national surveillance program of cirrhotic and noncirrhotic patients with chronic hepatitis C in Japan

H Yoshida, Y Shiratori, M Moriyama… - Annals of internal …, 1999 - acpjournals.org
Background: Previous studies on the effect of interferon therapy on the incidence of
hepatocellular carcinoma have not sufficiently assessed degree of liver fibrosis, a major risk …

[HTML][HTML] XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor

H Yoshida, T Matsui, A Yamamoto, T Okada, K Mori - Cell, 2001 - cell.com
In yeast, the transmembrane protein kinase/endoribonuclease Ire1p activated by
endoplasmic reticulum stress cleaves HAC1 mRNA, leading to production of the …

GEANT4—a simulation toolkit

…, DC Williams, D Wright, T Yamada, H Yoshida… - Nuclear instruments and …, 2003 - Elsevier
Geant4 is a toolkit for simulating the passage of particles through matter. It includes a
complete range of functionality including tracking, geometry, physics models and hits. The …

[HTML][HTML] Recent developments in Geant4

…, DM Wright, T Yamashita, J Yarba, H Yoshida - Nuclear instruments and …, 2016 - Elsevier
G eant 4 is a software toolkit for the simulation of the passage of particles through matter. It is
used by a large number of experiments and projects in a variety of application domains …

Histologic improvement of fibrosis in patients with hepatitis C who have sustained response to interferon therapy

…, M Sata, G Yamada, S Fujiyama, H Yoshida… - Annals of internal …, 2000 - acpjournals.org
Background: Short-term histologic improvement in hepatitis C-related hepatic fibrosis has
been noted in studies with more than 2 years of follow-up, but the long-term effects of …

Geant4 developments and applications

…, DC Williams, D Wright, H Yoshida - … on nuclear science, 2006 - ieeexplore.ieee.org
Geant4 is a software toolkit for the simulation of the passage of particles through matter. It is
used by a large number of experiments and projects in a variety of application domains …

OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis

YY Kong, H Yoshida, I Sarosi, HL Tan, E Timms… - Nature, 1999 - nature.com
The tumour-necrosis-factor-family molecule osteoprotegerin ligand (OPGL; also known as
TRANCE, RANKL and ODF) has been identified as a potential osteoclast differentiation …