User profiles for "author:George Fountzilas"
GEORGE FOUNTZILASProfessor Emeritus, Aristotle University of Thessaloniki Verified email at auth.gr Cited by 32130 |
Trastuzumab in the adjuvant treatment of early-stage breast cancer: a systematic review and meta-analysis of randomized controlled trials
Abstract Learning Objectives After completing this course, the reader will be able to:
Summarize the main characteristics and findings of randomized controlled trials evaluating …
Summarize the main characteristics and findings of randomized controlled trials evaluating …
Effects of KRAS, BRAF, NRAS, and PIK3CA mutations on the efficacy of cetuximab plus chemotherapy in chemotherapy-refractory metastatic colorectal cancer: a …
W De Roock, B Claes, D Bernasconi… - The lancet …, 2010 - thelancet.com
Background Following the discovery that mutant KRAS is associated with resistance to anti-
epidermal growth factor receptor (EGFR) antibodies, the tumours of patients with metastatic …
epidermal growth factor receptor (EGFR) antibodies, the tumours of patients with metastatic …
The upgraded role of HER3 and HER4 receptors in breast cancer
AK Koutras, G Fountzilas, KT Kalogeras… - Critical reviews in …, 2010 - Elsevier
The human epidermal growth factor receptor (HER) family comprises four homologous
members. The activation of these receptors affects essential tumorigenic processes and …
members. The activation of these receptors affects essential tumorigenic processes and …
[HTML][HTML] Prognostic significance of autoimmunity during treatment of melanoma with interferon
Background Immunotherapy for advanced melanoma induces serologic and clinical
manifestations of autoimmunity. We assessed the prognostic significance of autoimmunity in …
manifestations of autoimmunity. We assessed the prognostic significance of autoimmunity in …
Chemotherapy and radiotherapy in nasopharyngeal carcinoma: an update of the MAC-NPC meta-analysis
P Blanchard, A Lee, S Marguet, J Leclercq… - The lancet …, 2015 - thelancet.com
Background A previous individual patient data meta-analysis by the Meta-Analysis of
Chemotherapy in Nasopharynx Carcinoma (MAC-NPC) collaborative group to assess the …
Chemotherapy in Nasopharynx Carcinoma (MAC-NPC) collaborative group to assess the …
[HTML][HTML] Inherited mutations in 17 breast cancer susceptibility genes among a large triple-negative breast cancer cohort unselected for family history of breast cancer
Purpose Recent advances in DNA sequencing have led to the development of breast cancer
susceptibility gene panels for germline genetic testing of patients. We assessed the …
susceptibility gene panels for germline genetic testing of patients. We assessed the …
Neratinib after trastuzumab-based adjuvant therapy in HER2-positive breast cancer (ExteNET): 5-year analysis of a randomised, double-blind, placebo-controlled …
M Martin, FA Holmes, B Ejlertsen, S Delaloge… - The lancet …, 2017 - thelancet.com
Background ExteNET showed that 1 year of neratinib, an irreversible pan-HER tyrosine
kinase inhibitor, significantly improves 2-year invasive disease-free survival after …
kinase inhibitor, significantly improves 2-year invasive disease-free survival after …
Meta-analysis of chemotherapy in head and neck cancer (MACH-NC): An update on 107 randomized trials and 19,805 patients, on behalf of MACH-NC Group
B Lacas, A Carmel, C Landais, SJ Wong… - Radiotherapy and …, 2021 - Elsevier
Abstract Background and purpose The Meta-Analysis of Chemotherapy in squamous cell
Head and Neck Cancer (MACH-NC) demonstrated that concomitant chemotherapy (CT) …
Head and Neck Cancer (MACH-NC) demonstrated that concomitant chemotherapy (CT) …
Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer
CM Phelan, KB Kuchenbaecker, JP Tyrer, SP Kar… - Nature …, 2017 - nature.com
To identify common alleles associated with different histotypes of epithelial ovarian cancer
(EOC), we pooled data from multiple genome-wide genotyping projects totaling 25,509 EOC …
(EOC), we pooled data from multiple genome-wide genotyping projects totaling 25,509 EOC …
A common variant at the TERT-CLPTM1L locus is associated with estrogen receptor–negative breast cancer
Estrogen receptor (ER)-negative breast cancer shows a higher incidence in women of
African ancestry compared to women of European ancestry. In search of common risk alleles …
African ancestry compared to women of European ancestry. In search of common risk alleles …