User profiles for "author:Gareth Ambler"

Gareth Ambler

University College London
Verified email at ucl.ac.uk
Cited by 12255

Review and evaluation of penalised regression methods for risk prediction in low‐dimensional data with few events

M Pavlou, G Ambler, S Seaman, M De Iorio… - Statistics in …, 2016 - Wiley Online Library
Risk prediction models are used to predict a clinical outcome for patients using a set of
predictors. We focus on predicting low‐dimensional binary outcomes typically arising in …

[HTML][HTML] Sample size calculation for a stepped wedge trial

G Baio, A Copas, G Ambler, J Hargreaves, E Beard… - Trials, 2015 - Springer
Abstract Background Stepped wedge trials (SWTs) can be considered as a variant of a
clustered randomised trial, although in many ways they embed additional complications …

Microbleeds, cerebral hemorrhage, and functional outcome after stroke thrombolysis: individual patient data meta-analysis

A Charidimou, G Turc, C Oppenheim, S Yan, JF Scheitz… - Stroke, 2017 - Am Heart Assoc
Background and Purpose—We assessed whether the presence, number, and distribution of
cerebral microbleeds (CMBs) on pre-intravenous thrombolysis MRI scans of acute ischemic …

[HTML][HTML] Clinical features of vaccine-induced immune thrombocytopenia and thrombosis

S Pavord, M Scully, BJ Hunt, W Lester… - … England Journal of …, 2021 - Mass Medical Soc
Background Vaccine-induced immune thrombocytopenia and thrombosis (VITT) is a new
syndrome associated with the ChAdOx1 nCoV-19 adenoviral vector vaccine against severe …

The use of fractional polynomials to model continuous risk variables in epidemiology.

P Royston, G Ambler, W Sauerbrei - International journal of …, 1999 - academic.oup.com
BACKGROUND: The traditional method of analysing continuous or ordinal risk factors by
categorization or linear models may be improved. METHODS: We propose an approach …

[HTML][HTML] How to develop a more accurate risk prediction model when there are few events

M Pavlou, G Ambler, SR Seaman, O Guttmann, P Elliott… - Bmj, 2015 - bmj.com
How to develop a more accurate risk prediction model when there are few events | The BMJ
Skip to main content Intended for healthcare professionals Access provided by Google Indexer …

[HTML][HTML] Selective laser trabeculoplasty versus eye drops for first-line treatment of ocular hypertension and glaucoma (LiGHT): a multicentre randomised controlled trial

G Gazzard, E Konstantakopoulou, D Garway-Heath… - The Lancet, 2019 - thelancet.com
Background Primary open angle glaucoma and ocular hypertension are habitually treated
with eye drops that lower intraocular pressure. Selective laser trabeculoplasty is a safe …

Effect of robot-assisted radical cystectomy with intracorporeal urinary diversion vs open radical cystectomy on 90-day morbidity and mortality among patients with …

JWF Catto, P Khetrapal, F Ricciardi, G Ambler… - Jama, 2022 - jamanetwork.com
Importance Robot-assisted radical cystectomy is being performed with increasing frequency,
but it is unclear whether total intracorporeal surgery improves recovery compared with open …

Generic, simple risk stratification model for heart valve surgery

G Ambler, RZ Omar, P Royston, R Kinsman… - Circulation, 2005 - Am Heart Assoc
Background—Heart valve surgery has an associated in-hospital mortality rate of 4% to 8%.
This study aims to develop a simple risk model to predict the risk of in-hospital mortality for …

Ethnic group differences in overweight and obese children and young people in England: cross sectional survey

S Saxena, G Ambler, TJ Cole, A Majeed - Archives of Disease in …, 2004 - adc.bmj.com
Aims: To determine the percentage of children and young adults who are obese or
overweight within different ethnic and socioeconomic groups. Methods: Secondary analysis …