User profiles for "author:G. Rennert"

Gad Rennert

carmel medical center, technion, clalit, haifa, israel
Verified email at tx.technion.ac.il
Cited by 29611

Global implementation of genomic medicine: we are not alone

…, HL Rehm, MV Relling, G Rennert… - Science translational …, 2015 - science.org
Around the world, innovative genomic-medicine programs capitalize on singular capabilities
arising from local health care systems, cultural or political milieus, and unusual selected risk …

Beyond aspirin—cancer prevention with statins, metformin and bisphosphonates

N Gronich, G Rennert - Nature reviews Clinical oncology, 2013 - nature.com
Cancer risk reduction using pharmacological means is an attractive modern preventive
approach that supplements the classical behavioural prevention recommendations …

Genome-wide association scan identifies a colorectal cancer susceptibility locus on 11q23 and replicates risk loci at 8q24 and 18q21

…, J Vijayakrishnan, RS Houlston, G Rennert… - Nature …, 2008 - nature.com
In a genome-wide association study to identify loci associated with colorectal cancer (CRC)
risk, we genotyped 555,510 SNPs in 1,012 early-onset Scottish CRC cases and 1,012 …

[HTML][HTML] Statins and the risk of colorectal cancer

…, M Low, JK Greenson, G Rennert - … England Journal of …, 2005 - Mass Medical Soc
Background Statins are inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A reductase and
effective lipid-lowering agents. Statins inhibit the growth of colon-cancer cell lines, and …

Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes

…, MC Aldrich, WS Bush, A Tardon, G Rennert… - Nature …, 2017 - nature.com
Although several lung cancer susceptibility loci have been identified, much of the heritability
for lung cancer remains unexplained. Here 14,803 cases and 12,262 controls of European …

Network modeling links breast cancer susceptibility and centrosome dysfunction

…, KN Stevens, M Tewari, JS Ahn, G Rennert… - Nature …, 2007 - nature.com
Many cancer-associated genes remain to be identified to clarify the underlying molecular
mechanisms of cancer susceptibility and progression. Better understanding is also required …

Discovery of common and rare genetic risk variants for colorectal cancer

…, EA Platz, RL Prentice, E Pugh, L Raskin, G Rennert… - Nature …, 2019 - nature.com
To further dissect the genetic architecture of colorectal cancer (CRC), we performed whole-
genome sequencing of 1,439 cases and 720 controls, imputed discovered sequence …

A locus on 19p13 modifies risk of breast cancer in BRCA1 mutation carriers and is associated with hormone receptor–negative breast cancer in the general …

…, P Soucy, WS Rubinstein, A Arason, G Rennert… - Nature …, 2010 - nature.com
Germline BRCA1 mutations predispose to breast cancer. To identify genetic modifiers of this
risk, we performed a genome-wide association study in 1,193 individuals with BRCA1 …

Oral contraceptives and the risk of breast cancer in BRCA1 and BRCA2 mutation carriers

…, R Gershoni-Baruch, G Rennert… - Journal of the …, 2002 - academic.oup.com
Background: Oral contraceptive use has been associated with an increase in the risk of
breast cancer in young women. We examined whether this association is seen in women at …

[PDF][PDF] Breast Cancer Risk Following Bilateral Oophorectomy in BRCA1 and BRCA2 Mutation Carriers: An International Case-Control Study

…, R Gershoni-Baruch, E Friedman, G Rennert… - Journal of clinical …, 2005 - seom.org
Purpose The purpose of this study was to estimate the extent of protection offered against
breast cancer by prophylactic oophorectomy in carriers of BRCA1 or BRCA2 mutations and …