Bromodomain and extraterminal domain (BET) proteins are epigenetic readers that regulate
gene expression and are involved in cancer pathogenesis. Over the last years, several BET …

Extranodal marginal zone B-cell lymphoma is a discrete clinicopathological entity arising in
mucosa-associated lymphoid tissue (MALT) that has commanded increasing attention in …

Extranodal marginal zone (MZ) B-cell lymphomas of the mucosa-associated lymphoid tissue
(MALT) arise from lymphoid populations that are induced by chronic inflammation in …

Toll-like receptors (TLRs) sense microbial products and initiate adaptive immune responses
by activating dendritic cells (DCs). As pathogens may contain several TLR agonists, we …

Diffuse large B-cell lymphoma (DLBCL), the most common form of lymphoma in adulthood,
comprises multiple biologically and clinically distinct subtypes including germinal centre B …

The pathogenesis of chronic lymphocytic leukemia (CLL), the most common leukemia in
adults, is still largely unknown. The full spectrum of genetic lesions that are present in the …

The identification of new genetic lesions in chronic lymphocytic leukemia (CLL) prompts a
comprehensive and dynamic prognostic algorithm including gene mutations and …

The genetic lesions identified in chronic lymphocytic leukemia (CLL) do not entirely
recapitulate the disease pathogenesis and the development of serious complications, such …

A systematic characterization of the genetic alterations driving ALCLs has not been
performed. By integrating massive sequencing strategies, we provide a comprehensive …

Richter syndrome (RS) represents the development of diffuse large B-cell lymphoma in the
context of chronic lymphocytic leukemia. The scarcity of biologic information about RS has …