Nitric oxide is generated by the NO synthases, a family of isoenzymes expressed in a wide
range of mammalian cells. In the vascular and nervous systems distinct isoforms generate …

OBJECTIVE--To determine the efficacy and morbidity of fine loop diathermy excision of the
cervical transformation zone as applied to the management of outpatients with abnormal …

Objective To study whether intervention debulking surgery improves survival in patients with
advanced ovarian cancer who have bulky (> 2 cm) residual disease after primary surgery …

Thirty-six patients with epithelial ovarian cancer, incompletely resected at primary
laparotomy, were treated with one of two intensive cis-platinum-based combination …

Radical, curative surgery may not be considered in elderly patients with gynecologic cancer,
yet the morbidity for this population from radiotherapy and cytotoxics may be high. This study …

Unlike many other malignancies, overall survival for women with epithelial ovarian cancer
has improved only modestly over the last half-century. The perspectives presented here …

Background Pyruvate kinase isoenzyme M2-PK is instrumental to tumour metabolism and
hence over-expressed in tumour cells leading to detectable plasma concentrations …

Since borderline ovarian tumours came into light in the early 1970s, they continued to
present a challenge to doctors and patients equally. The majority of affected women present …

A retrospective survey of 38 ovarian cancer patients who developed radiologically confirmed
intestinal obstruction was performed. Twenty-six patients underwent surgery. In the surgical …

Thirty patients with symptomatic, progressive squamous cell carcinoma of the uterine cervix
no longer amenable to surgery or radiotherapy were entered in a phase II study of …