The genetics of alcoholism is at a pivotal point in its history. Decades of study of alcoholics,
their families, and controls have revealed an increasingly sophisticated clinical picture in …

The recent progress in harnessing the efficient and precise method of DNA editing provided
by CRISPR/Cas9 is one of the most promising major advances in the field of gene therapy …

Aggressive behavior has been defined in numerous ways to include behaviors ranging from
the milder forms of aggression such as throwing a temper tantrum or pouting to the more …

OBJECTIVE: To determine the most highly expressed microRNAs (miRNAs) in human
blastocysts and to compare miRNAs in euploid versus aneuploid embryos and in male …

• The association of the A1 allele of the D 2 dopamine receptor gene with alcoholism was
examined by comparing 32 unrelated white alcoholics with 25 unrelated white controls and …

The transmissibilities of 11 human craniofacial dimensions are estimated by path analysis
based upon familial correlations obtained in four different populations. Estimates from both …

PURPOSE The status of p53 in a tumor can be inferred by next-generation sequencing
(NGS) or by immunohistochemistry (IHC). We examined the association between p53 IHC …

Preeclampsia is a cardiovascular disorder of late pregnancy that is, commonly characterized
by hypertension, renal structural damage and dysfunction, and fetal growth restriction …

Individual mutations in the tumor suppressor TP53 alter p53 protein function. Some
mutations create a non‑functional protein, whereas others confer oncogenic activity, which …

Background Successfully combining targeted agents with chemotherapy is an important
future goal for cancer therapy. However, an improvement in patient outcomes requires an …