[HTML][HTML] Osteoporosis in the European Union: medical management, epidemiology and economic burden: a report prepared in collaboration with the International …

E Hernlund, A Svedbom, M Ivergård, J Compston… - Archives of …, 2013 - Springer
This report describes the epidemiology, burden, and treatment of osteoporosis in the 27
countries of the European Union (EU27). Introduction Osteoporosis is characterized by …

[HTML][HTML] Induction of mitochondrial dysfunction as a strategy for targeting tumour cells in metabolically compromised microenvironments

X Zhang, M Fryknäs, E Hernlund, W Fayad… - Nature …, 2014 - nature.com
Abnormal vascularization of solid tumours results in the development of microenvironments
deprived of oxygen and nutrients that harbour slowly growing and metabolically stressed …

[HTML][HTML] 3-Bromopyruvate as inhibitor of tumour cell energy metabolism and chemopotentiator of platinum drugs

LS Ihrlund, E Hernlund, O Khan, MC Shoshan - Molecular oncology, 2008 - Elsevier
Tumour cells depend on aerobic glycolysis for adenosine triphosphate (ATP) production,
making energy metabolism an interesting therapeutic target. 3-Bromopyruvate (BP) has …

Cisplatin and oxaliplatin toxicity: importance of cochlear kinetics as a determinant for ototoxicity

V Hellberg, I Wallin, S Eriksson… - Journal of the …, 2009 - academic.oup.com
Background Cisplatin is a cornerstone anticancer drug with pronounced ototoxicity, whereas
oxaliplatin, a platinum derivative with a different clinical profile, is rarely ototoxic. This …

Potentiation of chemotherapeutic drugs by energy metabolism inhibitors 2‐deoxyglucose and etomoxir

E Hernlund, LS Ihrlund, O Khan, YO Ates… - … journal of cancer, 2008 - Wiley Online Library
Inhibition of energy production as a strategy for potentiation of anticancer chemotherapy was
investigated using 1 glycolysis inhibitor and 1 fatty acid β‐oxidation inhibitor—2 …

Quality of life after hip, vertebral, and distal forearm fragility fractures measured using the EQ-5D-3L, EQ-VAS, and time-trade-off: results from the ICUROS

A Svedbom, F Borgström, E Hernlund, O Ström… - Quality of Life …, 2018 - Springer
Abstract Introduction The International Costs and Utilities Related to Osteoporotic fractures
Study is a multinational observational study set up to describe the costs and quality of life …

Ovarian carcinoma cells with low levels of β-F1-ATPase are sensitive to combined platinum and 2-deoxy-d-glucose treatment

E Hernlund, E Hjerpe, E Åvall-Lundqvist… - Molecular cancer …, 2009 - AACR
We have here examined chemopotentiating effects of glycolysis inhibitor 2-deoxy-d-glucose
(DG) in two epithelial ovarian carcinoma (EOC) cell lines and 17 freshly isolated ascitic EOC …

Heterogeneity in survival with immune checkpoint inhibitors and its implications for survival extrapolations: a case study in advanced melanoma

V Federico Paly, M Kurt, L Zhang… - MDM Policy & …, 2022 - journals.sagepub.com
Background Survival heterogeneity and limited trial follow-up present challenges for
estimating lifetime benefits of oncology therapies. This study used CheckMate 067 …

[PDF][PDF] Epidemiology and economic burden of osteoporosis in Greece

A Svedbom, E Hernlund, M Ivergard, J Compston… - Arch …, 2013 - researchgate.net
This report describes epidemiology, burden, and treatment of osteoporosis in Greece.
Introduction Osteoporosis is characterized by reduced bone mass and disruption of bone …

Treatment patterns, health care utilization, and costs of ovarian cancer in Central and Eastern Europe using a Delphi panel based on a retrospective chart review

K Kim, E Hernlund, Z Hernadi, J Révész… - International Journal of …, 2013 - ijgc.bmj.com
Objective Despite the considerable disease burden of ovarian cancer, there were no cost
studies in Central and Eastern Europe. This study aimed to describe treatment patterns …