Molecular analysis of the A322D mutation in the GABAA receptor α1‐subunit causing juvenile myoclonic epilepsy

K Krampfl, S Maljevic, P Cossette… - European Journal of …, 2005 - Wiley Online Library
Juvenile myoclonic epilepsy (JME) belongs to the most common forms of hereditary
epilepsy, the idiopathic generalized epilepsies. Although the mode of inheritance is usually …

Generation of MCF-7 cells with aggressive metastatic potential in vitro and in vivo

E Ziegler, MT Hansen, M Haase, G Emons… - Breast cancer research …, 2014 - Springer
Epithelial-mesenchymal transition (EMT) is a cellular development program characterized
by loss of cell adhesion and increased cell mobility. It is essential for numerous processes …

Kisspeptin-10 inhibits bone-directed migration of GPR54-positive breast cancer cells: Evidence for a dose–window effect

T Olbrich, E Ziegler, G Türk, A Schubert, G Emons… - Gynecologic …, 2010 - Elsevier
OBJECTIVES: The KiSS-1 gene product is absent or expressed at low level in metastatic
breast cancer compared with their nonmetastatic counterparts. A deca-peptide derived from …

Kisspeptin-10 inhibits stromal-derived factor 1–induced invasion of human endometrial cancer cells

E Schmidt, M Haase, E Ziegler, G Emons… - International Journal of …, 2014 - ijgc.bmj.com
Objectives The cross talk between metastatic cancer cells and target sites is critical for the
development and progression of metastases. Disruption of this interaction will allow to …

[HTML][HTML] Militarinone A induces differentiation in PC12 cells via MAP and Akt kinase signal transduction pathways

U Riese, E Ziegler, M Hamburger - FEBS letters, 2004 - Elsevier
The fungal metabolite militarinone A (MILI A) promotes neurite outgrowth in PC12 cells. This
study was conducted to investigate the signaling pathways involved in the cellular …

[HTML][HTML] Antiproliferative effects of kisspeptin‑10 depend on artificial GPR54 (KISS1R) expression levels

E Ziegler, T Olbrich, G Emons… - Oncology …, 2013 - spandidos-publications.com
Kisspeptins are peptides derived from the metastasis suppressor gene KISS1 interacting
with GPR54 as their corresponding receptor. The KISS1/GPR54 system is one regulator of …

Contents of essential oil, valerenic acids and extractives in different parts of the rootstock of medicinal valerian (Valeriana officinalis L. sl)

M Penzkofer, E Ziegler, H Heuberger - Journal of Applied Research on …, 2014 - Elsevier
In 2008, a breeding project was started with the aim to develop one or several varieties of
Valeriana officinalis L. sl with a coarse root system and reliable ingredient contents …

Increased mycophenolic acid exposure in stable kidney transplant recipients on tacrolimus as compared with those on sirolimus: implications for pharmacokinetics

F Braun, H Schöcklmann, E Ziegler… - Clinical …, 2009 - Wiley Online Library
The pharmacokinetics of mycophenolic acid (MPA) was studied in 23 kidney transplant
recipients with stable, long‐term graft function who were receiving mycophenolate mofetil …

Interaction of androsterone and progesterone with inhibitory ligand-gated ion channels: a patch clamp study

E Ziegler, M Bodusch, Y Song, K Jahn, H Wolfes… - Naunyn-Schmiedeberg's …, 2009 - Springer
Gamma-aminobutyric acid receptor type A (GABA A) receptor channels mediate fast
inhibitory neurotransmission throughout the central nervous system while the expression of …

[PDF][PDF] Pharmacological investigations on inhibitory ligand-gated ion channels using patch clamp technique in combination with an ultra-fast perfusion system

EV Ziegler - 2009 - elib.tiho-hannover.de
2. Materials and methods………… 25 2.1. Chemicals reagents and material s………… 25
2.2. Vectors………… 27 2.3. Prokaryotic cells………… 28 2.3. 1. Media and …