The purpose of this review was to evaluate whether the Penn Resiliency Program (PRP), a
group cognitive–behavioral intervention, is effective in targeting depressive symptoms in …

Cancer chemoprevention is defined as the use of natural, synthetic, or biologic chemical
agents to reverse, suppress, or prevent carcinogenic progression to invasive cancer. The …

Epidermal growth factor receptor inhibitors (EGFRIs) have demonstrated improved overall
survival in patients with non-small cell lung cancer, pancreatic cancer, and colorectal …

Background Two phase II trials in patients with previously-treated advanced non-small-cell
lung cancer suggested that gefitinib was efficacious and less toxic than was chemotherapy …

Abstract Background Severe coronavirus disease 2019 (Covid-19) is associated with
dysregulated inflammation. The effects of combination treatment with baricitinib, a Janus …

Abstract The Biomarker-integrated Approaches of Targeted Therapy for Lung Cancer
Elimination (BATTLE) trial represents the first completed prospective, biopsy-mandated …

Among the various polymorphs of carbon in inorganic form, such as diamond, graphite,
fullerene, and carbon nanotubes, a new polymorph, a 2D single graphene layer, has …

Purpose: Epithelial–mesenchymal transition (EMT) has been associated with metastatic
spread and EGF receptor (EGFR) inhibitor resistance. We developed and validated a robust …

Purpose Most crizotinib-treated patients with anaplastic lymphoma kinase gene (ALK)–
rearranged non–small-cell lung cancer (ALK-positive NSCLC) eventually experience …

Purpose Bevacizumab (Avastin; Genentech, South San Francisco, CA) is a recombinant,
humanized anti-vascular endothelial growth factor monoclonal antibody. Erlotinib HCl …