Background Incomplete excision of cervical precancer is associated with therapeutic failure
and is therefore considered as a quality indicator of clinical practice. Conversely, the risk of …

Please cite this paper as: Underwood M, Arbyn M, Parry‐Smith W, De Bellis‐Ayres S, Todd
R, Redman CWE, Moss EL. Accuracy of colposcopy‐directed punch biopsies: a systematic …

Background The human papillomavirus (HPV) vaccine is recommended for adolescent girls
in many European countries, however there is huge variation in vaccine uptake. Methods A …

Intestinal bacteria may modulate the risk of infection and graft-versus-host disease (GVHD)
after allogeneic hematopoietic stem cell transplantation (allo-HSCT). Allo-HSCT recipients …

Background The RTS, S/AS01 vaccine targets the circumsporozoite protein of Plasmodium
falciparum and has partial protective efficacy against clinical and severe malaria disease in …

Antimalarial drugs have thus far been chiefly derived from two sources—natural products
and synthetic drug-like compounds. Here we investigate whether antimalarial agents with …

Background: CA125 is a high molecular weight glycoprotein, which is expressed by a large
proportion of epithelial ovarian cancers. The sensitivity and specificity of CA125 are poor …

Microbial genomes can be assembled from short-read sequencing data, but the assembly
contiguity of these metagenome-assembled genomes is constrained by repeat elements …

Osmotic diarrhea is a prevalent condition in humans caused by food intolerance,
malabsorption, and widespread laxative use. Here, we assess the resilience of the gut …

In regions with high malaria endemicity, the withdrawal of chloroquine (CQ) as first-line
treatment of Plasmodium falciparum infections has typically led to the restoration of CQ …