DNA methylation, consisting of the addition of a methyl group at the fifth‐position of cytosine
in a CpG dinucleotide, is one of the most well‐studied epigenetic mechanisms in mammals …

Aims The International Endocervical Adenocarcinoma Criteria and Classification (IECC) was
recently proposed as an improved method for categorising endocervical adenocarcinoma …

Purpose Patients with prostate cancer on active surveillance are monitored by repeat
prostate specific antigen measurements, digital rectal examinations and prostate biopsies. A …

Aberrant DNA methylation is a hallmark of cancer and is an important potential biomarker.
Particularly, combined analysis of a panel of hypermethylated genes shows the most …

Aims To report novel observations in five mesonephric‐like adenocarcinomas (MLAs) of the
female genital tract. Methods and results We report two endometrial MLAs in association …

Background The development of noninvasive tests for the early detection of aggressive
prostate tumors is a major unmet clinical need. miRNAs are promising noninvasive …

The PROMISE diagnostic algorithm, which uses p53, mismatch repair (MMR) protein
immunohistochemistry, and DNA polymerase ε (POLE) exonuclease domain mutation …

Background Prevention of unnecessary biopsies and overtreatment of indolent disease
remains a challenge in the management of prostate cancer. Novel non-invasive tests that …

Purpose: Conventional clinical variables cannot accurately differentiate indolent from
aggressive prostate cancer in patients on active surveillance. We investigated promising …

CTNNB1 mutations and aberrant β-catenin expression have adverse prognosis in
endometrial endometrioid carcinoma, and recent evidence suggests a prognostic role of β …