Treatment correlates of successful outcomes in pulmonary multidrug-resistant tuberculosis: an individual patient data meta-analysis
N Ahmad, SD Ahuja, OW Akkerman, JWC Alffenaar… - The Lancet, 2018 - thelancet.com
Background Treatment outcomes for multidrug-resistant tuberculosis remain poor. We aimed
to estimate the association of treatment success and death with the use of individual drugs …
to estimate the association of treatment success and death with the use of individual drugs …
The use of 18F-FDG PET in the diagnosis of cardiac sarcoidosis: a systematic review and metaanalysis including the Ontario experience
G Youssef, E Leung, I Mylonas, P Nery… - Journal of nuclear …, 2012 - Soc Nuclear Med
Cardiac sarcoidosis is a potentially fatal complication of sarcoidosis. The 1993 guidelines of
the Ministry of Health, Labour, and Welfare (MHLW) of Japan have been used as the …
the Ministry of Health, Labour, and Welfare (MHLW) of Japan have been used as the …
Epigenetic regulation in human melanoma: past and future
The development and progression of melanoma have been attributed to independent or
combined genetic and epigenetic events. There has been remarkable progress in …
combined genetic and epigenetic events. There has been remarkable progress in …
A TALE nuclease architecture for efficient genome editing
Nucleases that cleave unique genomic sequences in living cells can be used for targeted
gene editing and mutagenesis. Here we develop a strategy for generating such reagents …
gene editing and mutagenesis. Here we develop a strategy for generating such reagents …
[PDF][PDF] Randomized trial of dose-dense versus conventionally scheduled and sequential versus concurrent combination chemotherapy as postoperative adjuvant …
ML Citron, DA Berry… - Journal of …, 2003 - mauriciolema.webhost4life.com
Purpose: Using a 2 2 factorial design, we studied the adjuvant chemotherapy of women with
axillary node–positive breast cancer to compare sequential doxorubicin (A), paclitaxel (T) …
axillary node–positive breast cancer to compare sequential doxorubicin (A), paclitaxel (T) …
Targeted genome editing across species using ZFNs and TALENs
Evolutionary studies necessary to dissect diverse biological processes have been limited by
the lack of reverse genetic approaches in most organisms with sequenced genomes. We …
the lack of reverse genetic approaches in most organisms with sequenced genomes. We …
[HTML][HTML] Efficacy of the herpes zoster subunit vaccine in adults 70 years of age or older
…, I Gorfinkel, T Korhonen, E Leung… - … England Journal of …, 2016 - Mass Medical Soc
Background A trial involving adults 50 years of age or older (ZOE-50) showed that the
herpes zoster subunit vaccine (HZ/su) containing recombinant varicella–zoster virus …
herpes zoster subunit vaccine (HZ/su) containing recombinant varicella–zoster virus …
The EML4‐ALK fusion gene is involved in various histologic types of lung cancers from nonsmokers with wild‐type EGFR and KRAS
DWS Wong, ELH Leung, KKT So, IYS Tam… - Cancer, 2009 - Wiley Online Library
BACKGROUND: The echinoderm microtubule‐associated protein‐like 4‐anaplastic
lymphoma kinase (EML4‐ALK) fusion gene resulting from the chromosome inversion inv …
lymphoma kinase (EML4‐ALK) fusion gene resulting from the chromosome inversion inv …
Critical role for β7 integrins in formation of the gut-associated lymphoid tissue
IMMUNE defence against pathogens entering the gut is accomplished by lymphocytes in the
gut-associated lymphoid tissue (GALT), a major compartment of the immune system1. The …
gut-associated lymphoid tissue (GALT), a major compartment of the immune system1. The …
[HTML][HTML] Effect of COVID-19 pandemic lockdowns on planned cancer surgery for 15 tumour types in 61 countries: an international, prospective, cohort study
J Glasbey, A Ademuyiwa, A Adisa, E AlAmeer… - The Lancet …, 2021 - thelancet.com
Background Surgery is the main modality of cure for solid cancers and was prioritised to
continue during COVID-19 outbreaks. This study aimed to identify immediate areas for …
continue during COVID-19 outbreaks. This study aimed to identify immediate areas for …