Malignant ascites-derived exosomes of ovarian carcinoma patients contain CD24 and EpCAM
S Runz, S Keller, C Rupp, A Stoeck, Y Issa… - Gynecologic …, 2007 - Elsevier
OBJECTIVE.: CD24 is an established marker for poor prognosis in ovarian and other
carcinomas. Acquisition of cytoplasmic CD24, as opposed to membranous expression, has …
carcinomas. Acquisition of cytoplasmic CD24, as opposed to membranous expression, has …
Systemic presence and tumor-growth promoting effect of ovarian carcinoma released exosomes
S Keller, AK König, F Marmé, S Runz, S Wolterink… - Cancer letters, 2009 - Elsevier
Exosomes are membrane vesicles that are released from many different cell types. Tumor
derived-exosomes play a role in immune suppression. We hypothesized that in ovarian …
derived-exosomes play a role in immune suppression. We hypothesized that in ovarian …
Epigenetic silencing of argininosuccinate synthetase confers resistance to platinum‐induced cell death but collateral sensitivity to arginine auxotrophy in ovarian …
LJ Nicholson, PR Smith, L Hiller… - … journal of cancer, 2009 - Wiley Online Library
Evidence indicates that acquired resistance of cancers to chemotherapeutic agents can
occur via epigenetic mechanisms. Down‐regulation of expression of argininosuccinate …
occur via epigenetic mechanisms. Down‐regulation of expression of argininosuccinate …
Psychometric validation of the European organisation for research and treatment of cancer quality of life questionnaire-endometrial cancer module (EORTC QLQ …
E Greimel, A Nordin, A Lanceley, CL Creutzberg… - European journal of …, 2011 - Elsevier
AIM: A validation study was conducted to evaluate the psychometric properties of the
European Organisation for Research and Treatment of Cancer (EORTC) Quality of Life …
European Organisation for Research and Treatment of Cancer (EORTC) Quality of Life …
Cold atmospheric plasma (CAP) and CAP-stimulated cell culture media suppress ovarian cancer cell growth–a putative treatment option in ovarian cancer therapy
D Koensgen, I Besic, D Guembel, A Kaul… - Anticancer …, 2017 - ar.iiarjournals.org
Background/Aim: Ovarian cancer (OC) is a gynecologic tumor with poor prognosis. Despite
radical cytoreductive surgery and platinum-based adjuvant systemic treatment, OC will …
radical cytoreductive surgery and platinum-based adjuvant systemic treatment, OC will …
Polo-like kinase Plk2 is an epigenetic determinant of chemosensitivity and clinical outcomes in ovarian cancer
N Syed, HM Coley, J Sehouli, D Koensgen, A Mustea… - Cancer research, 2011 - AACR
Resistance to platinum-and taxane-based chemotherapy remains a major clinical
impediment to effective management of epithelial ovarian cancer (EOC). To gain insights …
impediment to effective management of epithelial ovarian cancer (EOC). To gain insights …
Expression analysis and RNA localization of PAI-RBP1 (SERBP1) in epithelial ovarian cancer: association with tumor progression
D Koensgen, A Mustea, I Klaman, P Sun… - Gynecologic …, 2007 - Elsevier
OBJECTIVE: The plasminogen activator system (PA) plays an important role in invasion and
metastasis of solid tumors. The PA Inhibitor type 1 (PAI-1) is the main physiologic regulator …
metastasis of solid tumors. The PA Inhibitor type 1 (PAI-1) is the main physiologic regulator …
[HTML][HTML] Heat shock protein HSP27 secretion by ovarian cancer cells is linked to intracellular expression levels, occurs independently of the endoplasmic reticulum …
MB Stope, G Klinkmann, K Diesing, D Koensgen… - Disease …, 2017 - hindawi.com
The heat shock protein HSP27 has been correlated in ovarian cancer (OC) patients with
aggressiveness and chemoresistance and, therefore, represents a promising potential …
aggressiveness and chemoresistance and, therefore, represents a promising potential …
Expression and localization of e-cadherin in epithelial ovarian cancer
Background: Findings for the role of E-cadherin in ovarian cancer (OC) are controversial.
The aim of this study was to analyze the expression and prognostic role of E-cadherin in OC …
The aim of this study was to analyze the expression and prognostic role of E-cadherin in OC …
[HTML][HTML] Plasma treatment of ovarian cancer cells mitigates their immuno-modulatory products active on THP-1 monocytes
S Bekeschus, CP Wulf, E Freund, D Koensgen… - Plasma, 2018 - mdpi.com
Cancers modulate their microenvironment to favor their growth. In particular, monocytes and
macrophages are targeted by immuno-modulatory molecules installed by adjacent tumor …
macrophages are targeted by immuno-modulatory molecules installed by adjacent tumor …