Background: In patients with Ovarian Cancer (OvCa) exosomes released by tumor cells are
present in the plasma and could be involved in tumor progression. This study examines the …

Objectives The external, two-center validation of the IOTA ADNEX model for differential
diagnosis of adnexal tumors. Methods A total of 204 patients with adnexal masses (134 …

Although both incidence and aggressiveness of ovarian malignancy rise with age, the exact
reason for this tendency, in particular the contribution of senescent cells, remains elusive. In …

Gastrointestinal cancers metastasize into the peritoneal cavity in a process controlled by
peritoneal mesothelial cells (HPMCs). In this paper we examined if senescent HPMCs can …

Purpose After the seeding ovarian cancer cells into the peritoneal cavity, ascitic fluid creates
a microenvironment in which these cells can survive and disseminate. The exact nature of …

It is believed that senescent cells contribute to the progression of primary and metastatic
tumors, however, the exact mechanisms of this activity remain elusive. In this report we show …

The exact role of malignant ascites in the development of intraperitoneal ovarian cancer
metastases remains unclear. In this report we sought to establish if ascites can determine …

Although undifferentiated tumors are the most lethal among all ovarian cancer histotypes,
the exact reasons for this situation are unclear. This report was aimed at investigating …

Aim The aim of this study was to evaluate the role of the serum osteopontin (OPN) level as a
biomarker for discriminating between malignant and benign ovarian tumors. Furthermore …

The cancer-promoting activity of senescent peritoneal mesothelial cells (HPMCs) has
already been well evidenced both in vitro and in vivo. Here we sought to determine if …