The known breast cancer susceptibility polymorphisms in FGFR2, TNRC9/TOX3, MAP3K1,
LSP1, and 2q35 confer increased risks of breast cancer for BRCA1 or BRCA2 mutation …

Purpose We assessed the associations between population-based polygenic risk scores
(PRS) for breast (BC) or epithelial ovarian cancer (EOC) with cancer risks for BRCA1 and …

Introduction Previous studies have demonstrated that common breast cancer susceptibility
alleles are differentially associated with breast cancer risk for BRCA1 and/or BRCA2 …

Genome-wide association studies of breast cancer have identified multiple single nucleotide
polymorphisms (SNPs) that are associated with increased breast cancer risks in the general …

Background Comparative studies on the use of meshes and acellular dermal matrices
(ADM) in implant-based breast reconstruction (IBBR) have not yet been performed. Methods …

Background Breast cancer is characterized by malignant transformation of epithelial cells,
but stromal cells also play an important role in tumorigenesis. While tumor-derived …

Recent studies have identified single nucleotide polymorphisms (SNPs) that significantly
modify breast cancer risk in BRCA1 and BRCA2 mutation carriers. Since these risk modifiers …

Endometriosis is an estrogen-dependent gynecological disease causing pelvic pain and
infertility. Impaired estrogen metabolism is thought to play a pivotal role in the pathogenesis …

Background The birth year‐dependent onset of breast cancer (BC) in BRCA 1/2 mutation
carriers suggests a risk‐modifying role for reproductive and life style factors. We therefore …

We investigated the prevalence of germline BRCA mutations in a population‐based cohort
of Austrian women diagnosed with ovarian cancer and its association with family history of …