Background: Cancer patients receiving chemotherapy experience thromboembolic
complications associated with the use of long-term indwelling central venous catheters …

Squamous cell cancer of the esophagus is the most common cancer among black South
African males, and 60% of patients present with localized inoperable disease. Combined …

Here we describe the synthesis and structure–activity relationship for a class of pyrazoline-
containing dihydroquinolone negative allosteric modulators of the NMDA receptor that show …

Fibroblast growth factors (FGFs) are key regulators of the remarkable regenerative capacity
of the liver. Mice lacking FGF receptors 1 and 2 (Fgfr1 and Fgfr2) in hepatocytes are …

Long non‐coding RNA s (lnc RNA s) have been implicated in the regulation of chromatin
conformation and epigenetic patterns. lnc RNA expression levels are widely taken as an …

The syntheses of bis (triazolium) carbazole precursors and their corresponding coinage
metal (Au, Ag) complexes are reported. For alkylated triazolium salts, di‐or tetranuclear …

The aim of this multicentric phase II study was to investigate the efficacy and toxicity of a
combination of chemotherapy containing paclitaxel (Taxol®) and a novel compound, a …

NAMFIS (N MR A nalysis of M olecular F lexibility I n S olution) has been applied to curcumin
dissolved in DMSO. Quantitative 1H–1H distance constraints reduce a pool of candidate …

Mycobacterium tuberculosis and the fast-growing species Mycobacterium abscessus are
two important human pathogens causing persistent pulmonary infections that are difficult to …

To evaluate the single agent activity, pharmacokinetics and tolerability of the novel tubulin
targeted agent vinflunine (VFL)(320 mg m− 2 q 21 days) as second-line chemotherapy in …