Synthetic progestogens (progestins) have been linked to increased breast cancer risk;
however, the role of endogenous progesterone in breast physiology and carcinogenesis is …

The incidence of testicular cancer has been increasing over the past several decades in
many developed countries. The reasons for the increases are unknown because the risk …

In 2018, there will be approximately 22,240 new cases of ovarian cancer diagnosed and
14,070 ovarian cancer deaths in the United States. Herein, the American Cancer Society …

An understanding of the origin of cancer is critical for cancer prevention and treatment.
Complex biological mechanisms promote carcinogenesis, and there is increasing evidence …

Purpose An understanding of the etiologic heterogeneity of ovarian cancer is important for
improving prevention, early detection, and therapeutic approaches. We evaluated 14 …

Background A comprehensive characterization of the effects of cigarette smoke on systemic
soluble immune/inflammatory markers may provide insight into the mechanisms through …

Background Regular aspirin use is associated with reduced risk of several malignancies.
Epidemiologic studies analyzing aspirin, nonaspirin nonsteroidal anti-inflammatory drug …

Background Nonsteroidal anti-inflammatory drugs (NSAIDs) have been shown to reduce
chronic inflammation and risk of many cancers, but their effect on risk of hepatocellular …

Incidence rates of testicular cancer in Northern European and North American countries
have been widely reported, whereas rates in other populations, such as Eastern Europe …

PURPOSE To determine whether recommended amounts of leisure-time physical activity
(ie, 7.5-15 metabolic equivalent task [MET] hours/week) are associated with lower cancer …