Different combined oral contraceptives and the risk of venous thrombosis: systematic review and network meta-analysis

BH Stegeman, M de Bastos, FR Rosendaal… - Bmj, 2013 - bmj.com
Objective To provide a comprehensive overview of the risk of venous thrombosis in women
using different combined oral contraceptives. Design Systematic review and network meta …

Combined oral contraceptives: venous thrombosis

M de Bastos, BH Stegeman… - Cochrane Database …, 2014 - cochranelibrary.com
Background Combined oral contraceptive (COC) use has been associated with venous
thrombosis (VT)(ie, deep venous thrombosis and pulmonary embolism). The VT risk has …

Does thrombophilia testing help in the clinical management of patients?

S Middeldorp… - British journal of …, 2008 - Wiley Online Library
Thrombophilia can be identified in about half of all patients presenting with venous
thrombosis. Testing has increased tremendously for various indications, but whether the …

High levels of factor IX increase the risk of venous thrombosis

AH Vlieg, IK van der Linden, RM Bertina… - Blood, The Journal …, 2000 - ashpublications.org
Elevated plasma levels of factor VIII (> 150 IU/dL) are an important risk factor for deep vein
thrombosis (DVT). Factor VIII is the cofactor of factor IXa in the activation of factor X. The risk …

[PDF][PDF] Meta-analysis of 65,734 individuals identifies TSPAN15 and SLC44A2 as two susceptibility loci for venous thromboembolism

M Germain, DI Chasman, H De Haan, W Tang… - The American Journal of …, 2015 - cell.com
Venous thromboembolism (VTE), the third leading cause of cardiovascular mortality, is a
complex thrombotic disorder with environmental and genetic determinants. Although several …

Low levels of tissue factor pathway inhibitor (TFPI) increase the risk of venous thrombosis

A Dahm, A van Hylckama Vlieg, B Bendz, F Rosendaal… - Blood, 2003 - ashpublications.org
There is now strong experimental evidence that tissue factor pathway inhibitor (TFPI) is a
critical inhibitor to modulate tissue factor–induced coagulation, but the role of TFPI as a risk …

The risk of deep venous thrombosis associated with injectable depot–medroxyprogesterone acetate contraceptives or a levonorgestrel intrauterine device

A van Hylckama Vlieg, FM Helmerhorst… - … , and vascular biology, 2010 - Am Heart Assoc
Objective—To assess the risk of venous thrombosis associated with nonoral contraceptives
(ie, injectable depot–medroxyprogesterone acetate contraceptives, hormone …

Genomic and transcriptomic association studies identify 16 novel susceptibility loci for venous thromboembolism

S Lindström, LU Wang, EN Smith… - Blood, The Journal …, 2019 - ashpublications.org
Venous thromboembolism (VTE) is a significant contributor to morbidity and mortality. To
advance our understanding of the biology contributing to VTE, we conducted a genome …

[HTML][HTML] Long-term survival in a large cohort of patients with venous thrombosis: incidence and predictors

LE Flinterman, A van Hylckama Vlieg… - PLoS …, 2012 - journals.plos.org
Background Venous thrombosis is a common disease with a high mortality rate shortly after
the event. However, details on long-term mortality in these patients are lacking. The aim of …

Lower risk of cardiovascular events in postmenopausal women taking oral estradiol compared with oral conjugated equine estrogens

NL Smith, M Blondon, KL Wiggins… - JAMA internal …, 2014 - jamanetwork.com
Importance Little is known about the comparative cardiovascular safety of oral hormone
therapy products, which impedes women from making informed safety decisions about …