[HTML][HTML] A phase 3 trial of bevacizumab in ovarian cancer
TJ Perren, AM Swart, J Pfisterer… - … England Journal of …, 2011 - Mass Medical Soc
Background Angiogenesis plays a role in the biology of ovarian cancer. We examined the
effect of bevacizumab, the vascular endothelial growth factor inhibitor, on survival in women …
effect of bevacizumab, the vascular endothelial growth factor inhibitor, on survival in women …
Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer
TERT-locus SNPs and leukocyte telomere measures are reportedly associated with risks of
multiple cancers. Using the Illumina custom genotyping array iCOGs, we analyzed∼ 480 …
multiple cancers. Using the Illumina custom genotyping array iCOGs, we analyzed∼ 480 …
Genomic and epigenetic alterations deregulate microRNA expression in human epithelial ovarian cancer
MicroRNAs (miRNAs) are an abundant class of small noncoding RNAs that function as
negative gene regulators. miRNA deregulation is involved in the initiation and progression …
negative gene regulators. miRNA deregulation is involved in the initiation and progression …
MicroRNA Microarray Identifies Let-7i as a Novel Biomarker and Therapeutic Target in Human Epithelial Ovarian Cancer
N Yang, S Kaur, S Volinia, J Greshock, H Lassus… - Cancer research, 2008 - AACR
Abstract MicroRNAs (miRNA) are approximately 22-nucleotide noncoding RNAs that
negatively regulate protein-coding gene expression in a sequence-specific manner via …
negatively regulate protein-coding gene expression in a sequence-specific manner via …
GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer
PDP Pharoah, YY Tsai, SJ Ramus, CM Phelan… - Nature …, 2013 - nature.com
Genome-wide association studies (GWAS) have identified four susceptibility loci for
epithelial ovarian cancer (EOC), with another two suggestive loci reaching near genome …
epithelial ovarian cancer (EOC), with another two suggestive loci reaching near genome …
Common variants at 19p13 are associated with susceptibility to ovarian cancer
Epithelial ovarian cancer (EOC) is the leading cause of death from gynecological
malignancy in the developed world, accounting for 4% of the deaths from cancer in women …
malignancy in the developed world, accounting for 4% of the deaths from cancer in women …
Exome sequencing identifies FANCM as a susceptibility gene for triple-negative breast cancer
JI Kiiski, LM Pelttari, S Khan… - Proceedings of the …, 2014 - National Acad Sciences
Inherited predisposition to breast cancer is known to be caused by loss-of-function mutations
in BRCA1, BRCA2, PALB2, CHEK2, and other genes involved in DNA repair. However, most …
in BRCA1, BRCA2, PALB2, CHEK2, and other genes involved in DNA repair. However, most …
Surveillance for endometrial cancer in hereditary nonpolyposis colorectal cancer syndrome
L Renkonen‐Sinisalo, R Bützow… - … journal of cancer, 2007 - Wiley Online Library
The estimated lifetime risk for endometrial carcinoma (EC) in hereditary nonpolyposis
colorectal cancer syndrome (HNPCC) is 32–60%, thus supporting surveillance. The survival …
colorectal cancer syndrome (HNPCC) is 32–60%, thus supporting surveillance. The survival …
[HTML][HTML] Epigenetic analysis leads to identification of HNF1B as a subtype-specific susceptibility gene for ovarian cancer
HNF1B is overexpressed in clear cell epithelial ovarian cancer, and we observed epigenetic
silencing in serous epithelial ovarian cancer, leading us to hypothesize that variation in this …
silencing in serous epithelial ovarian cancer, leading us to hypothesize that variation in this …
Updating on primary fallopian tube carcinoma
A Riska, A Leminen - Acta Obstetricia et Gynecologica …, 2007 - Taylor & Francis
Primary fallopian tube carcinoma (PFTC) is rare, constituting about 1% of female genital tract
malignancies, and little is known about its etiological, protective, risk or prognostic factors …
malignancies, and little is known about its etiological, protective, risk or prognostic factors …