Clinical management of metastatic colorectal cancer in the era of precision medicine

F Ciardiello, D Ciardiello, G Martini… - CA: a cancer journal …, 2022 - Wiley Online Library
Colorectal cancer (CRC) represents approximately 10% of all cancers and is the second
most common cause of cancer deaths. Initial clinical presentation as metastatic CRC …

Hepatocellular carcinoma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

A Vogel, A Cervantes, I Chau, B Daniele… - Annals of …, 2018 - annalsofoncology.org
The incidence of hepatocellular carcinoma (HCC) has been rising worldwide over the last
20 years and is expected to increase until 2030 in some countries including the United …

Integration of oncology and palliative care: a Lancet Oncology Commission

S Kaasa, JH Loge, M Aapro, T Albreht… - The lancet …, 2018 - thelancet.com
Full integration of oncology and palliative care relies on the specific knowledge and skills of
two modes of care: the tumour-directed approach, the main focus of which is on treating the …

[HTML][HTML] ESMO consensus guidelines for the management of patients with metastatic colorectal cancer

E Van Cutsem, A Cervantes, R Adam, A Sobrero… - Annals of …, 2016 - Elsevier
Colorectal cancer (CRC) is one of the most common malignancies in Western countries.
Over the last 20 years, and the last decade in particular, the clinical outcome for patients with …

[HTML][HTML] A phase 3 trial of bevacizumab in ovarian cancer

TJ Perren, AM Swart, J Pfisterer… - … England Journal of …, 2011 - Mass Medical Soc
Background Angiogenesis plays a role in the biology of ovarian cancer. We examined the
effect of bevacizumab, the vascular endothelial growth factor inhibitor, on survival in women …

Rectal cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

R Glynne-Jones, L Wyrwicz, E Tiret… - Annals of …, 2017 - annalsofoncology.org
The incidence of rectal cancer in the European Union is $125 000 per year, ie $35% of the
total colorectal cancer incidence, reflecting 15–25 cases/100000 population per year and is …

[HTML][HTML] Capecitabine as adjuvant treatment for stage III colon cancer

C Twelves, A Wong, MP Nowacki, M Abt… - … England Journal of …, 2005 - Mass Medical Soc
Background Intravenous bolus fluorouracil plus leucovorin is the standard adjuvant
treatment for colon cancer. The oral fluoropyrimidine capecitabine is an established …

[HTML][HTML] Standard chemotherapy with or without bevacizumab for women with newly diagnosed ovarian cancer (ICON7): overall survival results of a phase 3 …

AM Oza, AD Cook, J Pfisterer, A Embleton… - The Lancet …, 2015 - thelancet.com
Background The ICON7 trial previously reported improved progression-free survival in
women with ovarian cancer with the addition of bevacizumab to standard chemotherapy …

Randomized phase III study of panitumumab with fluorouracil, leucovorin, and irinotecan (FOLFIRI) compared with FOLFIRI alone as second-line treatment in patients …

M Peeters, TJ Price, A Cervantes… - Journal of clinical …, 2010 - ascopubs.org
Purpose Panitumumab is a fully human anti–epidermal growth factor receptor (EGFR)
monoclonal antibody that improves progression-free survival (PFS) in chemotherapy …

[PDF][PDF] OPTIMOX1: a randomized study of FOLFOX4 or FOLFOX7 with oxaliplatin in a stop-and-go fashion in advanced colorectal cancer—a GERCOR study

C Tournigand, A Cervantes, A Figer, G Lledo… - Journal of clinical …, 2006 - academia.edu
Purpose In metastatic colorectal cancer, a combination of leucovorin (LV) and fluorouracil
(FU) with oxaliplatin (FOLFOX) 4 is a standard first-line regimen. The cumulative …