User profiles for "author:Ahmed Elattar"
 | Ahmed ElattarPan Birmingham Gynaecological Cancer Centre Verified email at nhs.net Cited by 1673 |
Optimal primary surgical treatment for advanced epithelial ovarian cancer
A Elattar, A Bryant, BA Winter‐Roach… - Cochrane database …, 2011 - cochranelibrary.com
Background Ovarian cancer is the sixth most common cancer among women. In addition to
diagnosis and staging, primary surgery is performed to achieve optimal cytoreduction …
diagnosis and staging, primary surgery is performed to achieve optimal cytoreduction …
Surgical cytoreduction for recurrent epithelial ovarian cancer
T Al Rawahi, AD Lopes, RE Bristow… - Cochrane Database …, 2013 - cochranelibrary.com
Background The standard management of primary ovarian cancer is optimal cytoreductive
surgery followed by platinum‐based chemotherapy. Most women with primary ovarian …
surgery followed by platinum‐based chemotherapy. Most women with primary ovarian …
Impact of residual disease as a prognostic factor for survival in women with advanced epithelial ovarian cancer after primary surgery
Background Ovarian cancer is the seventh most common cancer among women and a
leading cause of death from gynaecological malignancies. Epithelial ovarian cancer is the …
leading cause of death from gynaecological malignancies. Epithelial ovarian cancer is the …
Development of a functional assay for homologous recombination status in primary cultures of epithelial ovarian tumor and correlation with sensitivity to poly (ADP …
A Mukhopadhyay, A Elattar, A Cerbinskaite… - Clinical cancer …, 2010 - AACR
Abstract Purpose: Poly (ADP-ribose) polymerase (PARP) inhibitors selectively target
homologous recombination (HR)–defective cells and show good clinical activity in …
homologous recombination (HR)–defective cells and show good clinical activity in …
Clinicopathological features of homologous recombination–deficient epithelial ovarian cancers: sensitivity to PARP inhibitors, platinum, and survival
A Mukhopadhyay, ER Plummer, A Elattar, S Soohoo… - Cancer research, 2012 - AACR
Up to 50% of epithelial ovarian cancers (EOC) display defects in the homologous
recombination (HR) pathway. We sought to determine the ramifications of the homologous …
recombination (HR) pathway. We sought to determine the ramifications of the homologous …
Androgen receptor expression is a biological marker for androgen sensitivity in high grade serous epithelial ovarian cancer
A Elattar, KG Warburton, A Mukhopadhyay… - Gynecologic …, 2012 - Elsevier
OBJECTIVES: In the present study we explore the effects of androgens and anti-androgens
on primary cultures of EOC cells. We also investigate the effects of chemotherapy on AR …
on primary cultures of EOC cells. We also investigate the effects of chemotherapy on AR …
[HTML][HTML] The use of ovarian cancer cells from patients undergoing surgery to generate primary cultures capable of undergoing functional analysis
RL O′ Donnell, A McCormick, A Mukhopadhyay… - PloS one, 2014 - journals.plos.org
The use of cell lines or animal models has significant disadvantages when dealing with a set
of heterogeneous diseases such as epithelial ovarian cancer. This has clinical relevance in …
of heterogeneous diseases such as epithelial ovarian cancer. This has clinical relevance in …
Complete cytoreduction after five or more cycles of neo-adjuvant chemotherapy confers a survival benefit in advanced ovarian cancer
Objectives To assess the impact of 5 or more cycles of neoadjuvant chemotherapy (NACT)
and cytoreductive outcomes on overall survival (OS) in patients undergoing interval …
and cytoreductive outcomes on overall survival (OS) in patients undergoing interval …
Maintaining surgical care delivery during the COVID-19 pandemic: A comparative cohort study at a tertiary gynecological cancer centre
Background Surgery is the cornerstone of gynecological cancer management, but inpatient
treatment may expose both patients and healthcare staff to COVID-19 infections. Plans to …
treatment may expose both patients and healthcare staff to COVID-19 infections. Plans to …
The NICE classification for 'Ultra‐radical (extensive) surgery for advanced ovarian cancer'guidance does not meaningfully predict postoperative complications: a …
Objective To determine which descriptors of cytoreductive surgical extent in advanced
ovarian cancer (AOC) best predict postoperative morbidity. Design Retrospective notes …
ovarian cancer (AOC) best predict postoperative morbidity. Design Retrospective notes …