Gallbladder cancer is a malignancy of biliary tract which is infrequent in developed countries
but common in some specific geographical regions of developing countries. Late diagnosis …

There are many ways to deliver drugs into the body, viz oral (through swallowing), sub
mucosal (through buccal and sublingual mucosa), parenteral (through injection) …

Abstract PI3K-AKT/mTOR signaling pathway represents an essential signaling mechanism
for mammalian enzyme-related receptors in transducing signals or biological processes …

Background Ovarian cancer has a poor prognosis, with just 40% of patients surviving 5
years. We designed this trial to establish the effect of early detection by screening on ovarian …

Background Ovarian cancer has a high case–fatality ratio, with most women not diagnosed
until the disease is in its advanced stages. The United Kingdom Collaborative Trial of …

Background Ovarian cancer continues to have a poor prognosis with the majority of women
diagnosed with advanced disease. Therefore, we undertook the UK Collaborative Trial of …

Mutations in FUS cause amyotrophic lateral sclerosis (ALS), including some of the most
aggressive, juvenile-onset forms of the disease. FUS loss-of-function and toxic gain-of …

Importance Thrombosis with thrombocytopenia syndrome (TTS) has been reported after
vaccination with the SARS-CoV-2 vaccines ChAdOx1 nCov-19 (Oxford–AstraZeneca) and …

Mutations in the RNA binding protein FUS cause amyotrophic lateral sclerosis (ALS), a fatal
adult motor neuron disease. Decreased expression of SMN causes the fatal childhood motor …

Background The increase in the worldwide incidence of endometrial cancer relates to rising
obesity, falling fertility, and the ageing of the population. Transvaginal ultrasound (TVS) is a …