Background Ovarian clear-cell and endometrioid carcinomas may arise from endometriosis,
but the molecular events involved in this transformation have not been described. Methods …

Background Granulosa-cell tumors (GCTs) are the most common type of malignant ovarian
sex cord–stromal tumor (SCST). The pathogenesis of these tumors is unknown. Moreover …

Ran (Ras-related nuclear protein) GTPase is a member of the Ras superfamily. Like all the
GTPases, Ran cycles between an active (GTP-bound) and inactive (GDP-bound) state …

Chronic myelogenous leukemia (CML) is a human disease associated with a consistent
chromosomal translocation that results in sequences from the c-abl locus on chromosome 9 …

TP53 mutations are ubiquitous in high‐grade serous ovarian carcinomas (HGSOC), and the
presence of TP53 mutation discriminates between high and low‐grade serous carcinomas …

We studied the whole-genome point mutation and structural variation patterns of 133 tumors
(59 high-grade serous (HGSC), 35 clear cell (CCOC), 29 endometrioid (ENOC), and 10 …

Melanoma is an immunogenic cancer with a high response rate to immune checkpoint
inhibitors (ICIs). It harbors a high mutation burden compared with other cancers and, as a …

Epithelial ovarian cancer (EOC) cell lines are useful tools for the molecular and biological
characterization of ovarian cancer. The use of an in vitro multidimensional (3‐D) culture …

Dear Editor: Epithelial ovarian cancer (EOC) is the most lethal gynecologic malignancy.
EOCs originate from either the surface epithelium itself or from the crypts or inclusion cysts …

The cell surface nucleotidase CD73 is an immunosuppressive enzyme involved in tumor
progression and metastasis. Although preclinical studies suggest that CD73 can be targeted …