[HTML][HTML] Muscle wasting and sarcopenia in heart failure—the current state of science

A Lena, MS Anker, J Springer - International journal of molecular sciences, 2020 - mdpi.com
Sarcopenia is primarily characterized by skeletal muscle disturbances such as loss of
muscle mass, quality, strength, and physical performance. It is commonly seen in elderly …

[HTML][HTML] miR-203 represses 'stemness' by repressing ΔNp63

AM Lena, R Shalom-Feuerstein… - Cell Death & …, 2008 - nature.com
The epidermis, the outer layer of the skin composed of keratinocytes, is a stratified
epithelium that functions as a barrier to protect the organism from dehydration and external …

[HTML][HTML] Health and social problems of the elderly: A cross-sectional study in Udupi Taluk, Karnataka

A Lena, K Ashok, M Padma, V Kamath… - Indian Journal of …, 2009 - journals.lww.com
Background: Change in socio-economic status and various health problems adversely affect
an individual's way of life during old age. Objectives: To study the health and social …

MicroRNAs, miR-154, miR-299-5p, miR-376a, miR-376c, miR-377, miR-381, miR-487b, miR-485-3p, miR-495 and miR-654-3p, mapped to the 14q32. 31 locus …

A Formosa, EK Markert, AM Lena, D Italiano… - Oncogene, 2014 - nature.com
Abstract miRNAs act as oncogenes or tumor suppressors in a wide variety of human
cancers, including prostate cancer (PCa). We found a severe and consistent downregulation …

[PDF][PDF] MiR-203 controls proliferation, migration and invasive potential of prostate cancer cell lines

G Viticchiè, AM Lena, A Latina, A Formosa… - Cell cycle, 2011 - researchgate.net
Prostate cancer (PCa) is the most frequent and age-related cancer in men: about 20% of the
worldwide male population will develop this kind of tumor during their lifetime and 2–3% will …

[HTML][HTML] Hypertension delays viral clearance and exacerbates airway hyperinflammation in patients with COVID-19

…, JP Albrecht, J Eils, S Hadzibegovic, A Lena… - Nature …, 2021 - nature.com
Abstract In coronavirus disease 2019 (COVID-19), hypertension and cardiovascular
diseases are major risk factors for critical disease progression. However, the underlying …

Recent advances in cardio‐oncology: a report from the 'Heart Failure Association 2019 and World Congress on Acute Heart Failure 2019'

MS Anker, S Hadzibegovic, A Lena… - ESC heart …, 2019 - Wiley Online Library
While anti‐cancer therapies, including chemotherapy, immunotherapy, radiotherapy, and
targeted therapy, are constantly advancing, cardiovascular toxicity has become a major …

DNA methylation silences miR-132 in prostate cancer

A Formosa, AM Lena, EK Markert, S Cortelli, R Miano… - Oncogene, 2013 - nature.com
Silencing of microRNAs (miRNAs) by promoter CpG island methylation may be an important
mechanism in prostate carcinogenesis. To screen for epigenetically silenced miRNAs in …

MicroRNAs in human skin ageing

M Mancini, AM Lena, G Saintigny, C Mahé… - Ageing research …, 2014 - Elsevier
The skin protects humans from the surrounding environment. Tissues undergo continuous
renewal throughout an individual's lifetime; however, there is a decline in the regenerative …

p63–microRNA feedback in keratinocyte senescence

P Rivetti di Val Cervo, AM Lena… - Proceedings of the …, 2012 - National Acad Sciences
We investigated the expression of microRNAs (miRNAs) associated with replicative
senescence in human primary keratinocytes. A cohort of miRNAs up-regulated in …