Androgen receptor inhibits estrogen receptor-α activity and is prognostic in breast cancer
There is emerging evidence that the balance between estrogen receptor-α (ERα) and
androgen receptor (AR) signaling is a critical determinant of growth in the normal and …
androgen receptor (AR) signaling is a critical determinant of growth in the normal and …
Induction of epithelial–mesenchymal transition (EMT) in breast cancer cells is calcium signal dependent
Signals from the tumor microenvironment trigger cancer cells to adopt an invasive
phenotype through epithelial–mesenchymal transition (EMT). Relatively little is known …
phenotype through epithelial–mesenchymal transition (EMT). Relatively little is known …
ORAI1-mediated calcium influx in lactation and in breast cancer
The entry of calcium into the mammary epithelial cell from the maternal plasma (ie, calcium
influx mechanisms) during lactation is poorly understood. As alterations in calcium channels …
influx mechanisms) during lactation is poorly understood. As alterations in calcium channels …
[HTML][HTML] Oncogenic stress sensitizes murine cancers to hypomorphic suppression of ATR
DW Schoppy, RL Ragland, O Gilad… - The Journal of …, 2012 - Am Soc Clin Investig
Oncogenic Ras and p53 loss-of-function mutations are common in many advanced sporadic
malignancies and together predict a limited responsiveness to conventional chemotherapy …
malignancies and together predict a limited responsiveness to conventional chemotherapy …
ORAI-mediated calcium entry: mechanism and roles, diseases and pharmacology
SJ Roberts-Thomson, AA Peters, DM Grice… - Pharmacology & …, 2010 - Elsevier
ORAI1 is a protein located on the plasma membrane that acts as a calcium channel.
Calcium enters via ORAI1 as a mechanism to refill the sarcoplasmic/endoplasmic reticulum …
Calcium enters via ORAI1 as a mechanism to refill the sarcoplasmic/endoplasmic reticulum …
Leader tracking in homogeneous vehicle platoons with broadcast delays
For vehicle platoons, the leader following control architecture is known to be capable of
achieving string stability while maintaining tight formations. In this paper, we study a variety …
achieving string stability while maintaining tight formations. In this paper, we study a variety …
[HTML][HTML] Artificial intelligence and interstitial lung disease: Diagnosis and prognosis
Interstitial lung disease (ILD) is now diagnosed by an ILD-board consisting of radiologists,
pulmonologists, and pathologists. They discuss the combination of computed tomography …
pulmonologists, and pathologists. They discuss the combination of computed tomography …
[HTML][HTML] Computer-aided diagnosis of pulmonary fibrosis using deep learning and CT images
A Christe, AA Peters, D Drakopoulos… - Investigative …, 2019 - journals.lww.com
Objectives The objective of this study is to assess the performance of a computer-aided
diagnosis (CAD) system (INTACT system) for the automatic classification of high-resolution …
diagnosis (CAD) system (INTACT system) for the automatic classification of high-resolution …
Calcium channel TRPV6 as a potential therapeutic target in estrogen receptor–negative breast cancer
AA Peters, PT Simpson, JJ Bassett, JM Lee… - Molecular cancer …, 2012 - AACR
Calcium signaling is a critical regulator of cell proliferation. Elevated expression of calcium
channels and pumps is a characteristic of some cancers, including breast cancer. We show …
channels and pumps is a characteristic of some cancers, including breast cancer. We show …
RNF4 and PLK1 are required for replication fork collapse in ATR-deficient cells
RL Ragland, S Patel, RS Rivard, K Smith… - Genes & …, 2013 - genesdev.cshlp.org
The ATR–CHK1 axis stabilizes stalled replication forks and prevents their collapse into DNA
double-strand breaks (DSBs). Here, we show that fork collapse in Atr-deleted cells is …
double-strand breaks (DSBs). Here, we show that fork collapse in Atr-deleted cells is …