Androgen receptor inhibits estrogen receptor-α activity and is prognostic in breast cancer

AA Peters, G Buchanan, C Ricciardelli, T Bianco-Miotto… - Cancer research, 2009 - AACR
There is emerging evidence that the balance between estrogen receptor-α (ERα) and
androgen receptor (AR) signaling is a critical determinant of growth in the normal and …

Induction of epithelial–mesenchymal transition (EMT) in breast cancer cells is calcium signal dependent

FM Davis, I Azimi, RA Faville, AA Peters, K Jalink… - Oncogene, 2014 - nature.com
Signals from the tumor microenvironment trigger cancer cells to adopt an invasive
phenotype through epithelial–mesenchymal transition (EMT). Relatively little is known …

ORAI1-mediated calcium influx in lactation and in breast cancer

D McAndrew, DM Grice, AA Peters, FM Davis… - Molecular cancer …, 2011 - AACR
The entry of calcium into the mammary epithelial cell from the maternal plasma (ie, calcium
influx mechanisms) during lactation is poorly understood. As alterations in calcium channels …

[HTML][HTML] Oncogenic stress sensitizes murine cancers to hypomorphic suppression of ATR

DW Schoppy, RL Ragland, O Gilad… - The Journal of …, 2012 - Am Soc Clin Investig
Oncogenic Ras and p53 loss-of-function mutations are common in many advanced sporadic
malignancies and together predict a limited responsiveness to conventional chemotherapy …

ORAI-mediated calcium entry: mechanism and roles, diseases and pharmacology

SJ Roberts-Thomson, AA Peters, DM Grice… - Pharmacology & …, 2010 - Elsevier
ORAI1 is a protein located on the plasma membrane that acts as a calcium channel.
Calcium enters via ORAI1 as a mechanism to refill the sarcoplasmic/endoplasmic reticulum …

Leader tracking in homogeneous vehicle platoons with broadcast delays

AA Peters, RH Middleton, O Mason - Automatica, 2014 - Elsevier
For vehicle platoons, the leader following control architecture is known to be capable of
achieving string stability while maintaining tight formations. In this paper, we study a variety …

[HTML][HTML] Artificial intelligence and interstitial lung disease: Diagnosis and prognosis

E Dack, A Christe, M Fontanellaz, L Brigato… - Investigative …, 2023 - journals.lww.com
Interstitial lung disease (ILD) is now diagnosed by an ILD-board consisting of radiologists,
pulmonologists, and pathologists. They discuss the combination of computed tomography …

[HTML][HTML] Computer-aided diagnosis of pulmonary fibrosis using deep learning and CT images

A Christe, AA Peters, D Drakopoulos… - Investigative …, 2019 - journals.lww.com
Objectives The objective of this study is to assess the performance of a computer-aided
diagnosis (CAD) system (INTACT system) for the automatic classification of high-resolution …

Calcium channel TRPV6 as a potential therapeutic target in estrogen receptor–negative breast cancer

AA Peters, PT Simpson, JJ Bassett, JM Lee… - Molecular cancer …, 2012 - AACR
Calcium signaling is a critical regulator of cell proliferation. Elevated expression of calcium
channels and pumps is a characteristic of some cancers, including breast cancer. We show …

RNF4 and PLK1 are required for replication fork collapse in ATR-deficient cells

RL Ragland, S Patel, RS Rivard, K Smith… - Genes & …, 2013 - genesdev.cshlp.org
The ATR–CHK1 axis stabilizes stalled replication forks and prevents their collapse into DNA
double-strand breaks (DSBs). Here, we show that fork collapse in Atr-deleted cells is …