OBJECTIVE: Testing for human papillomavirus (HPV) has been shown to increase the
sensitivity and negative predictive value for detection of high-grade cervical intraepithelial …

Cells differentiate when transcription factors bind accessible cis-regulatory elements to
establish specific gene expression programs. In differentiating embryonic stem cells …

Aims: The aim of this study was to obtain normative nasalance values for typically
developing Ugandan English-speaking children as a reference point for clinical practice and …

Background To evaluate the safety of several doses of a new thrombolytic, TNK tissue-
plasminogen activator (tPA), given as a single bolus to patients with acute myocardial …

OBJECTIVE: To ascertain the reliability of applying the WHO Cardiovascular Risk
Management Package by non-physician health-care workers (NPHWs) in typical primary …

Mutations in PKD1, which encodes polycystin-1 (PC1), contribute to> 85% of cases of
autosomal dominant polycystic kidney disease (ADPKD). The planar cell polarity (PCP) …

Aim of the study A tumour-free pathological resection margin of≥ 8 mm is considered state-
of-the-art. Available evidence is based on heterogeneous cohorts. This study was designed …

Objectives Time trends on the incidence and characteristics of invasive vulvar cancer in
Germany have so far been studied in few local population-and hospital based tumor …

Background Extramammary Paget disease (EMPD) is a very rare genital neoplasia
associated with a high frequency of local recurrences. Surgical excision is the standard …

Climate change affects both mental and physical health. Besides limiting the extent and
consequences of climate change, mitigation and adaptation measures can have additional …