Background Increases in mental health problems have been observed during the COVID-19
pandemic. The objectives were to examine the extent to which mental health symptoms …

We provide a brief synopsis of the unique physical and ecological attributes of sandy beach
ecosystems and review the main anthropogenic pressures acting on the world's single …

Previous organizational climate research, definitions, and measurement approaches are
reviewed and differentiated into 3 categories: a multiple measurement-organizational …

Objective To provide an update to “Surviving Sepsis Campaign Guidelines for Management
of Sepsis and Septic Shock: 2012”. Design A consensus committee of 55 international …

Molecular approaches to understanding the functional circuitry of the nervous system
promise new insights into the relationship between genes, brain and behaviour. The cellular …

The Cre/lox system is widely used in mice to achieve cell-type-specific gene expression.
However, a strong and universally responding system to express genes under Cre control is …

Neuroanatomically precise, genome-wide maps of transcript distributions are critical
resources to complement genomic sequence data and to correlate functional and genetic …

Background Few meta-analyses of randomised trials assess the quality of the studies
included. Yet there is increasing evidence that trial quality can affect estimates of …

Ascertaining the impact of uncharacterized perturbations on the cell is a fundamental
problem in biology. Here, we describe how a single assay can be used to monitor hundreds …

Background Somatic mutations in the Janus kinase 2 gene (JAK2) occur in many
myeloproliferative neoplasms, but the molecular pathogenesis of myeloproliferative …