Human cancer immunotherapy with antibodies to the PD-1 and PD-L1 pathway
KC Ohaegbulam, A Assal, E Lazar-Molnar… - Trends in molecular …, 2015 - cell.com
The programmed death 1 (PD-1) receptor and its ligands programmed death ligand 1 (PD-
L1) and PD-L2, members of the CD28 and B7 families, play critical roles in T cell coinhibition …
L1) and PD-L2, members of the CD28 and B7 families, play critical roles in T cell coinhibition …
[HTML][HTML] International Study to Evaluate PCR Methods for Detection of Trypanosoma cruzi DNA in Blood Samples from Chagas Disease Patients
…, G Russomando, P Büscher, A Assal… - PLoS neglected …, 2011 - journals.plos.org
Background A century after its discovery, Chagas disease still represents a major neglected
tropical threat. Accurate diagnostics tools as well as surrogate markers of parasitological …
tropical threat. Accurate diagnostics tools as well as surrogate markers of parasitological …
International survey on NAT testing of blood donations: expanding implementation and yield from 1999 to 2009
…, R Reimal, J Castren, M Naukkarinen, A Assal… - Vox …, 2012 - Wiley Online Library
Thirteen years ago, blood centres voluntarily started testing whole blood and platelet
apheresis donors using nucleic acid amplification technology (NAT). The first reports on the …
apheresis donors using nucleic acid amplification technology (NAT). The first reports on the …
Transfusion-transmitted hepatitis E virus infection in France
…, L Mouna, S Gross, P Bierling, A Assal… - Transfusion Medicine …, 2019 - Elsevier
There is growing concern regarding the risk of transfusion-transmitted (TT) hepatitis E. Since
the first described case in 2006, several TT hepatitis E have been reported to the French …
the first described case in 2006, several TT hepatitis E have been reported to the French …
Clinical features and outcomes of immune checkpoint inhibitor–associated AKI: a multicenter study
…, AC Shirali, A Kitchlu, S Shirazian, A Assal… - Journal of the …, 2020 - journals.lww.com
Background Despite increasing recognition of the importance of immune checkpoint
inhibitor–associated AKI, data on this complication of immunotherapy are sparse. Methods …
inhibitor–associated AKI, data on this complication of immunotherapy are sparse. Methods …
Emerging targets in cancer immunotherapy: beyond CTLA-4 and PD-1
A Assal, J Kaner, G Pendurti, X Zang - Immunotherapy, 2015 - Future Medicine
Manipulation of co-stimulatory or co-inhibitory checkpoint proteins allows for the reversal of
tumor-induced T-cell anergy observed in cancer. The field has gained credence given …
tumor-induced T-cell anergy observed in cancer. The field has gained credence given …
Outcomes of haploidentical vs matched sibling transplantation for acute myeloid leukemia in first complete remission
…, HL Wang, H Abdel-Azim, M Aljurf, A Assal… - Blood …, 2019 - ashpublications.org
HLA-haploidentical hematopoietic cell transplantation (Haplo-HCT) using
posttransplantation cyclophosphamide (PT-Cy) has improved donor availability. However, a …
posttransplantation cyclophosphamide (PT-Cy) has improved donor availability. However, a …
[HTML][HTML] Hepatitis E virus infections in blood donors, France
…, Y Piquet, K Sauné, F Abravanel, A Assal… - Emerging Infectious …, 2014 - ncbi.nlm.nih.gov
We screened plasma samples (minipools of 96 samples, corresponding to 53,234 blood
donations) from France that had been processed with solvent–detergent for hepatitis E virus …
donations) from France that had been processed with solvent–detergent for hepatitis E virus …
Estimated risk of Chikungunya viremic blood donation during an epidemic on Reunion Island in the Indian Ocean, 2005 to 2007
…, P Bernillon, I Quatresous, J Pillonel, A Assal… - …, 2008 - Wiley Online Library
BACKGROUND: Between 2005 and 2007, Chikungunya virus (CHIKV) caused a massive
epidemic on Reunion Island with a major peak in the number of cases in February 2006 …
epidemic on Reunion Island with a major peak in the number of cases in February 2006 …
Wide expression and significance of alternative immune checkpoint molecules, B7x and HHLA2, in PD-L1–negative human lung cancers
…, A Borczuk, M Janakiram, X Ren, J Lin, A Assal… - Clinical Cancer …, 2018 - AACR
Purpose: Immunotherapy targeting the PD-1/PD-L1 pathway has changed the treatment
landscape of non–small cell lung carcinoma (NSCLC). We demonstrated that HHLA2, a …
landscape of non–small cell lung carcinoma (NSCLC). We demonstrated that HHLA2, a …