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The following term was not found in PubMed: Grubis
Page 1
Studies on the partial characterization of extracted glycosaminoglycans from fish waste and its potentiality in modulating obesity through in-vitro and in-vivo.
V G, Das M, Zarei M, Vp M, Harohally NV, G SK. V G, et al. Among authors: g sk. Glycoconj J. 2022 Aug;39(4):525-542. doi: 10.1007/s10719-022-10077-5. Epub 2022 Aug 1. Glycoconj J. 2022. PMID: 35913650
The biological potential of the extracted glycoconjugate was assessed further through in-vitro and in-vivo studies. In-vitro biological activity showed good lipase inhibition (IC(50), 2.6 mg/mL) and bile acid binding properties (dose-dependent). ...
The biological potential of the extracted glycoconjugate was assessed further through in-vitro and in-vivo studies. In-vitro biological acti …
Stearyl palmitate a multi-target inhibitor against breast cancer: in-silico, in-vitro & in-vivo approach.
Ravi L, Kumar K A, Kumari G R S, S H, Sam Raj JB, R L, Chinnaiyan P, K C DJ, J K M, Sudhakara D, Dar MS, D M Y, G S. Ravi L, et al. Among authors: g s. J Biomol Struct Dyn. 2023 Sep 10:1-18. doi: 10.1080/07391102.2023.2255271. Online ahead of print. J Biomol Struct Dyn. 2023. PMID: 37691453
Further in-vitro MTT assay demonstrated that Stearyl Palmitate has a significant IC(50) value of 40 M against MCF-7 cells and >1000 M against L929 cells. ...It was observed that the fishes treated with IC(50) concentration of Stearyl Palmitate demonstrated 2x fol …
Further in-vitro MTT assay demonstrated that Stearyl Palmitate has a significant IC(50) value of 40 M against MCF-7 cells and >100 …
Comparative synthesis and characterization of nanocomposites using chemical and green approaches including a comparison study on in vivo and in vitro biological properties.
G S, S VP, E P, G A. G S, et al. Among authors: g a. Nanoscale Adv. 2022 Dec 13;5(3):767-785. doi: 10.1039/d2na00677d. eCollection 2023 Jan 31. Nanoscale Adv. 2022. PMID: 36756509 Free PMC article.
From the results of the cytotoxicity tests against MCF-7 cells and HaCaT cells using the nanocomposites, the IC(50) values of Salacia reticulata, green synthesized CS/SiO(2)/TiO(2)/CeO(2)/Fe(3)O(4) nanocomposites (CSTCF(G)), and chemically synthesized CS/SiO(2)/TiO(2)/CeO( …
From the results of the cytotoxicity tests against MCF-7 cells and HaCaT cells using the nanocomposites, the IC(50) values of Salacia …
Understanding the Combined Effects of High Glucose Induced Hyper-Osmotic Stress and Oxygen Tension in the Progression of Tumourigenesis: From Mechanism to Anti-Cancer Therapeutics.
G GK, Shinde PL, John S, C SK, Mishra R. G GK, et al. Cells. 2023 Mar 7;12(6):825. doi: 10.3390/cells12060825. Cells. 2023. PMID: 36980166 Free PMC article.
SENP1 was ascertained to restrict the abnormal SUMOylation of pH3(Ser10) in both normoxia and hypoxia, although not so efficiently in hypoxia, due to the opposing activity of SENP7. Co-treatment with Momordin Ic (MC), a natural SENP1 inhibitor, and Gallic Acid (GA), an inh …
SENP1 was ascertained to restrict the abnormal SUMOylation of pH3(Ser10) in both normoxia and hypoxia, although not so efficiently in hypoxi …
Novel Benzimidazole Derived Imine Ligand and Its Co(III) and Cu(II) Complexes as Anticancer Agents: Chemical Synthesis, DFT Studies, In Vitro and In Vivo Biological Investigations.
G P, Revanasiddappa HD, B J, T PB, Shivamallu C, Viswanath PM, Achar RR, Silina E, Stupin V, Manturova N, Shati AA, Alfaifi MY, Elbehairi SEI, Armaković SJ, Armaković S, Kollur SP. G P, et al. Pharmaceuticals (Basel). 2023 Jan 13;16(1):125. doi: 10.3390/ph16010125. Pharmaceuticals (Basel). 2023. PMID: 36678622 Free PMC article.
The biological results depicted that the compound C4, with molecular formula C(27)H(23)Cl(2)CoFN(5)O(3) exhibited profound anti-proliferative activity against the EAC cell line with a significant IC(50) value of 10 m when compared to its parent ligand and other remaining m …
The biological results depicted that the compound C4, with molecular formula C(27)H(23)Cl(2)CoFN(5)O(3) exhibited profound anti-proliferativ …
Mahamanalactone A, a new triterpenoid from Dysoxylum malabaricum bark: a case study for rapid identification of new metabolites via LC-HRMS profiling and database mining strategy.
Bhardwaj N, S S, Tripathi N, Kumar S, Lal UR, G R, Guru SK, Jain SK. Bhardwaj N, et al. Among authors: g r. Nat Prod Res. 2024 Jan 1:1-6. doi: 10.1080/14786419.2023.2298721. Online ahead of print. Nat Prod Res. 2024. PMID: 38163964
Cytotoxicity assessment revealed that the newly identified compound 5 exhibited a moderate cytotoxic profile (IC(50) 29 to 78 M) against a panel of cancer cell lines....
Cytotoxicity assessment revealed that the newly identified compound 5 exhibited a moderate cytotoxic profile (IC(50) 29 to 78 M) agai …
Anticancer potential of zinc oxide nanoparticles against cervical carcinoma cells synthesized via biogenic route using aqueous extract of Gracilaria edulis.
R MA, B G, M S MJ, G A, N S. R MA, et al. Among authors: g a. Mater Sci Eng C Mater Biol Appl. 2019 Oct;103:109840. doi: 10.1016/j.msec.2019.109840. Epub 2019 May 31. Mater Sci Eng C Mater Biol Appl. 2019. PMID: 31349511
Results of anticancer potential illustrated that ZnONPs exhibited cytotoxic effect against SiHa cells in a dose dependent manner with IC(50) value of 35 0.03 mug/ml. AO/EtBr dual staining, JC-1 staining, Hoechst 33258 nuclear staining and comet assay illustrated the ZnONPs …
Results of anticancer potential illustrated that ZnONPs exhibited cytotoxic effect against SiHa cells in a dose dependent manner with IC
Synthesis of novel pyrazolo[3,4-b]quinolinyl acetamide analogs, their evaluation for antimicrobial and anticancer activities, validation by molecular modeling and CoMFA analysis.
G JD, Poornachandra Y, Ratnakar Reddy K, Naresh Kumar R, Ravikumar N, Krishna Swaroop D, Ranjithreddy P, Shravan Kumar G, Nanubolu JB, Ganesh Kumar C, Narsaiah B. G JD, et al. Eur J Med Chem. 2017 Apr 21;130:223-239. doi: 10.1016/j.ejmech.2017.02.052. Epub 2017 Feb 22. Eur J Med Chem. 2017. PMID: 28254697
Based on these studies, compounds 5c, 5d, 5r and 7f were considered as promising and exhibited significant cytotoxicity with IC(50) values of <15 muM. The biological activity data was further validated by molecular modeling and CoMFA studies....
Based on these studies, compounds 5c, 5d, 5r and 7f were considered as promising and exhibited significant cytotoxicity with IC(50) v …