Table 3

Data on patients with recurrent endometrial cancer after fertility-sparing management

No.	Age	Grade	Time of first remission (months)	Pregnancy	DFS (months)	Time of second remission (months)	Re-treatment	Surgery	Reasons of surgery	Remission/ persistent/ progression	Second recur	Second DFS	Alive/ death	Follow-up
1	30	G1	6	Yes	16	6	Yes	No		Remission	No		Alive	2 years
2	35	G1	12	Yes	12	6	Yes	Yes	Do not want fertility preserving	Remission	No		Alive	6 months
3	33	G1	3	Yes	24	9	Yes			Remission	No		Alive	3 months Trying to conceive
4	30	G1	27	Yes	37		No	Yes	Do not want fertility preserving	Remission	No		Alive	3 years
5	28	G2	6	No	18	6	Yes	No		Persistent	Yes	10	Alive	3 months Refused surgery Re-treat
6	32	G1	9	No	6	12	Yes	No		Persistent	Yes	11	Alive	3 months Re-treat
7	33	G2	15	No	4	–	No	Yes	Do not want fertility preserving	Remission	No		Alive	2 years
8	33	G1	9	No	48	3	Yes	No		Remission	No		Alive	5 months Trying to conceive
9	36	G1	9	No	9	4	Yes	No		Persistent	No	3	Alive	3 months Re-treat 1000 mg
10	38	G2	12	No	4		Yes	Yes	Progression disease	Remission	No		Alive	Chemotherapy #6 (paclitaxel/ carboplatin) 3 years
11	32	G1	12	No	23		Yes	No		Persistent	No		Alive	5 years treatment underway Refused surgery
12	31	G1	3	No	23	55	Yes	No		Remission	No		Alive	2 years
13	38	G1	3	No	6	6	Yes	No		Remission	No		Alive	6 months Trying to conceive
14	33	G1	9	No	7	10	Yes	No		Persistent	No		Alive	1 year treatment underway Refused surgery
15	31	G1	3	No	25	48	Yes	No		Remission	No		Alive	Trying to conceive and f/u loss
16	33	G1	33	No	15		No	Yes	Do not want fertility preserving	Remission	No		Alive	3 years
17	35	G1	12	No	15		No	Yes	Do not want fertility preserving	Remission	No		Alive	3 years
18	31	G1	6	No	9		Yes	No		Persistent	No		Alive	7 months treatment underway