Table 1

Demographic and clinicopathological characteristics of included studies

First authorYearCountryInstitutionYears recruitingNMedian age, years* (range)PMPStageLNDRTCTHTMedian follow-up, months* (range)
IIIIIIIV
Agarwal et al6 2017IndiaAmrita Institute of Medical Sciences2005–201628N/AN/AN/AN/AN/AN/AN/AN/A
Amant et al 7 2007BelgiumKatholieke University Leuven1986–20053144 (18–60)81%220456007N/A
Beck et al8 2012USACleveland Clinic, Roswell Park, Magee1986–200242 44.8 (27–73)N/A2818395414 130
Berchuck et al9 1990USAMemorial Sloan Kettering1970–19842248N/A191200330N/A
Cheng et al10 2011USAMD Anderson1995–20067443.5 (22–68)82%N/A18932776 (2–444)
Chu et al 11 2003USAYale Universtity1978–20032245.5 (19–76)72.7%1704171013100 (2–258)
Evans et al12 1982USAMD AndersonN/A1139 (20–60)91%72020821N/A
Feng et al14 2011ChinaFudan University1992–20075743 (19-63)N/A45120036647068 (17–140)
Gaducci et al15 1996ItalyMutlicenter (Italy)1980–19942644 (18–68)N/A19142745192 (4–167)
Huang et al16 1996TaiwanNational Taiwan University1965–199417 43.5 (24–75)85%708214110 48.1 (15–173)
Li et al5 2005USAJohns Hopkins, UCLA, UTSW, Jeffersonn/a3646 (26–50) for OP, 45 (25–59) for bilateral salpingo-oophorectomy80.5%36000N/A40834.8 for ovarian preservation and 60 for bilateral salpingo-oophorectomy
Malouf et al13 2009FranceInstitut Gustav1977–20075447 (25–73)76%4860041431058 (3–348)
Mansi et al19 1990UKRoyal Marsden Hospital1973–19878 37 (30–50)75%6011030045 (8–128)
Norris et al20 1966USAArmed Forces DatabaseN/A18N/AN/AN/AN/AN/AN/AN/AN/A
Stewart et al18 2018USAUniversity of Washington1985–2014112 48.5 (22–87)N/A49820364*1*28*55 (1–325)
Yoon et al3 2013South KoreaSamsung Medical Center, Asan Medical Center1990–201211445 (18–74)77.2%929494512201246 (0.5–251)
Zhou et al17 2015ChinaXiamen Cancer Center1991–201311441 (19–58)86%77122237136561140 (3–172)
Total1965–201378647253105240113145142
  • BOLD: mean,

  • *Information on adjuvant treatment available for 51 patients.

  • CT, Chemotherapy; HT, hormonal therapy; LND, lymphadenectomy; PMP, premenopausal; RT, radiation therapy.