Table 1

Basic characteristics of patients with early-stage endometrial cancer who were in remission and attempting to conceive

		Total (n=49)	Pregnant (n=22)	Non-pregnant (n=27)	P values
Age of initial treatment, years	Median (range)	37 (28–45)	37 (29–41)	37.0 (28–45)	0.68*
BMI, kg/m²	Median (range)	22.7 (18.5–43.5)	22.0 (19.2–43.6)	23.5 (17.9–46.3)	0.26*
Parity	n (%)				0.16†
0		44 (89.8)	18 (81.8)	26 (96.3)
1≤		5 (10.2)	4 (18.2)	1 (3.7)
Presumed grade	n (%)				0.083†
G1		37 (75.5)	19 (90.5)	18 (66.7)
G2		11 (22.4)	2 (9.5)	9 (33.3)
PCO on ultrasonography	n (%)	33 (67.3)	15 (71.4)	18 (66.7)	0.72‡
Time of MPA treatment duration, months	Median (range)	12.2 (3–49)	11.9 (4–49)	12.0 (3–35)	0.93*
MPA dose					0.46‡
500 mg once daily	n (%)	33 (67.3)	17 (51.5)	16 (48.5)
1000 mg once daily	n (%)	16 (32.7)	10 (62.5)	6 (37.5)
Time to complete remission, months	Median (range)	6 (3–33)	6 (3–27)	9 (3–33)	0.32*
Initial CA 125	Median (range)	18 (3.9–58.9)	18.0 (11.4–58.9)	18.0 (3.9–55.7)	0.32*
CA 125 at the end of treatment	Median (range)	13.9 (1.2–30.1)	13.9 (1.2–30.1)	13.2 (6.3–29.7)	0.30*
Number of D&Cs	Median (range)	4 (2–7)	4 (2–7)	4 (2–7)	0.51*
Initial endometrium, mm	Median (range)	9.0	9.7 (4.4–18.0)	8.0 (3–18)	0.32*
Endometrium at the end of the treatment, mm	Median (range)	4 (2.3–10)	4.3 (2.3–7.0)	4.0 (2.5–10)	0.91*
Superficial myometrium invasion in MRI					0.67†
Yes	n (%)	6 (14.0)	4 (66.7)	2 (33.3%)
No	n (%)	37 (86.0)	20 (54.1)	17 (45.9)
Recurrence	n (%)	18 (36.7)	4 (18.2)	14 (51.9)	0.007†
Time of treatment end to recur, months	Median (range)	15.0 (4–48)	26.0 (20–38)	12.0 (4–48)	0.001§

*Mann-Whitney U test.
†Fisher’s exact test.
‡χ² test.
§Log-rank test.
BMI, body mass index; CA, cancer antigen; D&C, dilatation and curettage; MPA, medroxyprogesterone acetate; PCO, polycystic ovary.