Analysis | No. of studies | No. of patients | HR (95% CI) | P value | Model | Heterogeneity (I2 %/P) | Harbord test (P) |
Age (≤55Y vs. >55Y) | 5 | 343 | 0.73(0.40 to 1.33) | 0.31 | F | 0.0/0.97 | 0.39 |
Tumor size (≤4cm vs. >4cm) | 4 | 290 | 1.76(0.90 to 3.41) | 0.10 | F | 0.0/0.94 | 0.45 |
FIGO stage (I+II vs. III+IV) | 3 | 240 | 1.96(0.85 to 4.53) | 0.11 | F | 0.0/0.62 | 0.32 |
Histological grade (G1+G2 vs. G3) | 3 | 208 | 1.95(0.82 to 4.64) | 0.13 | F | 0.0/0.65 | 0.79 |
Lymph node metastases (N0 vs. N1+N2) | 4 | 291 | 2.57(1.28 to 5.16) | 0.00 | F | 0.0/0.84 | 0.39 |
Hemoglobin (≤11.5g/dL vs. >11.5g/dL) | 3 | 226 | 0.90(0.43 to 1.91) | 0.79 | F | 0.0/0.50 | 0.96 |
Parametrial invasion (yes vs. no) | 3 | 226 | 1.46(0.69 to 3.10) | 0.33 | F | 0.56/0.10 | 0.52 |
F:fixed-effect model; FIGO:International Federation of Gynaecology and Obstetrics; No:number.