Multivariable logistic regression model estimating the odds ratio of targeted therapy utilization based on patient characteristics (2010–19)
| Covariates | Odds ratio (95% CI) | P value |
| Race and ethnicity (reference=Non-Hispanic white) | ||
| Non-Hispanic black | 0.77 (0.61 to 0.98) | 0.032 |
| Asian | 0.90 (0.68 to 1.18) | 0.44 |
| Hispanic | 0.88 (0.72 to 1.08) | 0.23 |
| Other and unknown | 0.27 (0.08 to 0.87) | 0.028 |
| Age group at diagnosis (reference=65–69 years) | ||
| 70–74 | 0.91 (0.79 to 1.04) | 0.18 |
| 75–79 | 0.59 (0.51 to 0.69) | <0.001 |
| 80–84 | 0.50 (0.42 to 0.59) | <0.001 |
| ≥85 | 0.34 (0.27 to 0.42) | <0.001 |
| Year of diagnosis (reference=2010) | ||
| 2011 | 1.23 (0.97 to 1.55) | 0.09 |
| 2012 | 1.31 (1.04 to 1.65) | 0.02 |
| 2013 | 1.89 (1.51 to 2.38) | <0.001 |
| 2014 | 1.95 (1.55 to 2.46) | <0.001 |
| 2015 | 2.08 (1.66 to 2.60) | <0.001 |
| 2016 | 2.29 (1.83 to 2.88) | <0.001 |
| 2017 | 2.88 (2.28 to 3.64) | <0.001 |
| 2018 | 2.87 (2.26 to 3.64) | <0.001 |
| 2019 | 2.39 (1.88 to 3.04) | <0.001 |
| Region at diagnosis (Reference=Midwest region) | ||
| Northeast | 1.40 (1.12 to 1.76) | 0.003 |
| South | 1.47 (1.17 to 1.84) | 0.001 |
| West | 1.49 (1.18 to 1.87) | <0.001 |
| Charlson Comorbidity Index (Reference=0) | ||
| 1 | 0.90 (0.79 to 1.02) | 0.09 |
| ≥2 | 0.68 (0.59 to 0.78) | <0.001 |