Table 1

Patient characteristics

Characteristicn%
Age, median (range)56 (38–71)
Histology
High-grade serous carcinoma15100.0
Initial FIGO stage
 IIIB320.0
 IIIC746.7
 IVA320.0
 IVB213.3
BRCA status
 Mutant746.7
 Wild-type853.3
HRD status
 HRD positive853.3
 HRD unknown746.7
Neoadjuvant chemotherapy
 Number of patients receiving chemotherapy15100.0
 Number of chemotherapy cycles, median (range)5 (4–7)
 Number of patients receiving bevacizumab640.0
 Number of bevacizumab cycles, median (range)4 (4–6)
 Mean duration of neoadjuvant chemotherapy, days (SD)91 (28)
 Mean duration from last neoadjuvant chemotherapy to IDS, days (SD)39 (17)
IDS details
 Mean operative time, minutes (SD)135 (32)
 Post-operative pathological staging
 Tumor limited to one ovary, ypT1a16.6
 Microscopic extrapelvic involvement, ypT3a16.6
 Macroscopic metastasis beyond the pelvis ≤2 cm, ypT3b853.3
 Macroscopic metastasis beyond the pelvis >2 cm, ypT3c533.3
 Complete peritoneal debulking1173.3
ICG fluorescence microscopy
 Mean number of ICG bolus per patient, n (SD)1.6 (0.5)
 Mean intraoperative fluorescence time per bolus, minutes (SD)3.59 (1.39)
 Mean fluorescence time per patient, minutes (SD)5.74 (2.4)
 Number of additional suspect peritoneal samples per patient, n (SD)2.6 (1.12)
Survival outcomes
 Relapse746.7
 Mean PFS, months (95% CI)34.2 (27.1 to 41.4)
 Death320
 Mean OS, months (95% CI)42.4 (37.1 to 47.7)
 Mean follow-up, months (95% CI)36.6 (32.2 to 40.9)
  • BRCA, BReast CAncer gene; CI, confidence interval; FIGO, International Federation of Gynecology and Obstetrics; HRD, homologous recombination deficiency; ICG, indocyanine green; IDS, interval debulking surgery; OS, overall survival; PFS, progression-free survival.