Predictors of positive nodes
| Univariate | Multivariate | |||
| OR (95% CI) | P value | OR (95% CI) | P value | |
| Age, years* | 0.978 (0.739 to 1.288) | 0.862 | – | – |
| BMI, kg/m2† | 0.95 (0.695 to 1.256) | 0.653 | – | – |
| Histology | 0.074 | 0.38 | ||
| Endometrioid | Reference | Reference | ||
| Non-endometrioid | 2.155 (0.929 to 5.002) | 0.571 (0.164 to 1.998) | ||
| FIGO grade | 0.005 | 0.48 | ||
| Grade 1 and 2 | Reference | Reference | ||
| Grade 3 | 2.706 (0.1.341 to 5.460) | 1.461 (0.504 to 4.238) | ||
| Depth of myometrial invasion | <0.001 | 0.009 | ||
| <50% | Reference | Reference | ||
| >50% | 6.875 (3.191 to 14.811) | 3.318 (1.357 to 8.150) | ||
| Cervical stromal involvement | 0.650 | – | ||
| No | Reference | – | ||
| Yes | 0.57 (0.240 to 2.412) | – | ||
| Adnexal/serosal involvement | 0.311 | – | ||
| No | Reference | – | ||
| Yes | 0.05 (0.001 to 65.560) | – | ||
| LVSI | <0.001 | <0.001 | ||
| No | Reference | Reference | ||
| Yes | 11.24 (5.108 to 24.731) | 6.584 (2.663 to 16.279) | ||
| Positive peritoneal washing | 0.690 | – | ||
| No | References | – | ||
| Yes | 0.06 (0.001 to 50.801) | – | ||
| POLE mutation | 0.969 | – | ||
| No | Reference | – | ||
| Yes | 1.032 (0.211 to 5.053) | – | ||
| dMMR/MSI-H | 0.733 | – | ||
| No | Reference | – | ||
| Yes | 1.140 (0.536 to 2.424) | – | ||
| p53 abnormal | 0.602 | – | ||
| No | Reference | – | ||
| Yes | 0.788 (0.322 to 1.928) | – | ||
| NSMP | 0.992 | – | ||
| No | Reference | – | ||
| Yes | 1.035 (0.523 to 2.048) | – | ||
*OR per 10-year increase in age.
†OR per 5-unit increase in BMI.
BMI, body mass index; dMMR/MSI-H, mismatch repair deficient/microsatellite instability high; FIGO, International Federation of Obstetrics and Gynecology; LVSI, lymphovascular space invasion; NSMP, non-specific mutational profile; p53 abn, p53 abnormal; POLE, polymerase-epsilon.