Baseline characteristics of the study population
| N=210 | |
| Age, years | 64 (56–73) |
| BMI, kg/m2 | 27 (23–30) |
| Histology | |
| Endometrioid | 178 (84.8%) |
| Non-endometrioid | 32 (15.2%) |
| FIGO grade | |
| Grade 1 | 33 (15.7%) |
| Grade 2 | 113 (53.8%) |
| Grade 3 | 64 (30.5%) |
| Myometrial invasion | |
| <50% | 132 (62.9%) |
| >50% | 78 (37.1%) |
| LVSI | |
| No | 147 (70.0%) |
| Focal | 14 (6.7%) |
| Substantial | 49 (23.3%) |
| Positive nodes | |
| No | 169 (80.5%) |
| Yes | 41 (19.5%) |
| Molecular classification | |
| dMMR/MSI-H | 57 (27.1%) |
| POLE mutated | 10 (4.8%) |
| p53 abnormal | 42 (20%) |
| NSMP | 101 (48.1%) |
Data are reported as median (range, 25% and 75% percentile); number (%).
BMI, body mass index; dMMR/MSI-H, mismatch repair deficient/microsatellite instability high; FIGO, International Federation of Obstetrics and Gynecology; LVSI, lymphovascular space invasion; NSMP, non-specific mutational profile; POLE, polymerase-epsilon.